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  • Samuel W. Gerritz, Christopher M. Cianci, +31 authors Mark Krystal
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2011 (First Publication: 13 September 2011)
  • Influenza nucleoprotein (NP) plays multiple roles in the virus life cycle, including an essential function in viral replication as an integral component of the ribonucleoprotein complex, associatingContinue Reading
  • Kenneth E. J. Dickinson, Richard B. Cohen, +7 authors James R. Powell
  • Chemistry, Medicine
  • British journal of pharmacology
  • 1994 (First Publication: 1 September 1994)
  • 1. This study compares the activity of BMS-180560 (2-butyl-1-chloro-1-[[1-[2-(2H-tetrazol-5-yl)phenyl]-1H-indol-4- yl]methyl]-1H-imidazole-5-carboxylic acid), an insurmountable angiotensin II (AII)Continue Reading
  • Richard D. Cramer, Michael A. Poss, Mark A. Hermsmeier, Thomas J. Caulfield, Mark C. Kowala, Maria T. Valentine
  • Chemistry, Medicine
  • Journal of medicinal chemistry
  • 1999 (First Publication: 1 September 1999)
  • The principle of bioisosterism-similarly shaped molecules are more likely to share biological properties than are other molecules-has long helped to guide drug discovery. An algorithmicContinue Reading