Michael A. Richmond

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Although MAP (mitogen-activated protein) kinases are implicated in cell proliferation and differentiation in many cell types, the role of MAP kinases in cardiac hypertrophy remains unclear. We examined the role of extracellular signal-regulated protein kinase (ERK), c-Jun N-terminal kinase (JNK) and p38 MAP kinase in angiotensin II (Ang II)-induced(More)
Everyone talks about software bloat, feature creep and the ever-increasing complexity of software. Each new version of a software package adds in new features. Very rarely, features are removed. But what really happens as software evolves? This animated film illustrates the evolution of PowerPointover seven versions from 1987-2001. With each version the(More)
In this work, we describe RapA-dependent polyadenylation of model RNA substrates and endogenous, RNA polymerase-associated nucleic acid fragments. We demonstrate that the Escherichia coli RNA polymerase obtained through the classic purification procedure carries endogenous RNA oligonucleotides, which, in the presence of ATP, are polyriboadenylated in a(More)
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