Michael A. Elliott

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BACKGROUND Obsessive-compulsive disorder (OCD) often responds inadequately to serotonin reuptake inhibitors (SRIs). A case series reported substantial response to once-weekly oral morphine. We conducted a placebo-controlled, double-blind trial to investigate whether once-weekly oral morphine is effective in SRI-resistant OCD. METHOD Subjects with(More)
BACKGROUND Adding the atypical neuroleptic risperidone to a serotonin reuptake inhibitor (SRI) has benefited patients with treatment-refractory obsessive-compulsive disorder (OCD). Since olanzapine and risperidone have similar serotonergic and dopaminergic receptor binding profiles, we tested the hypothesis that olanzapine augmentation would be beneficial(More)
Various studies suggest that selective serotonin reuptake inhibitors (SSRIs) may be useful in treating pathologic skin-picking. The authors investigated the effectiveness of fluoxetine in treating this behavior. Fifteen subjects with clinically significant skin-picking were recruited by newspaper advertisement. They received 6 weeks of open-label treatment(More)
BACKGROUND Compulsive shopping, a DSM-IV impulse-control disorder not otherwise specified, is characterized by preoccupation with shopping and inability to resist buying unneeded items, with resulting marked distress, social or occupational impairment, and financial and/or familial problems. Because an open-label trial suggested that fluovaxamine, a(More)
INTRODUCTION Small studies have suggested that intravenous clomipramine (CMI) may be more effective and induce faster improvement in obsessive-compulsive disorder than do orally administered serotonin reuptake inhibitors. OBJECTIVE To test these hypotheses, we conducted a randomized, double-blind, double-dummy study of pulse-loaded intravenous versus oral(More)
At present, there are myriad concerns about tourism and sustainability at cultural and natural world heritage sites. Based on an analysis of 811 evaluations written between 1980 and 2010 by two official advisory bodies to the World Heritage Committee, this paper charts the timing and extent to which such concerns have become central to assessing the value(More)
Despite enormous e orts the US Census missed enumerating some US residents and counted others twice or more as part of Census To evaluate the degree of net overcount undercount capture recapture techniques similar to those used in wildlife population estimation Seber can be employed These techniques typically rely on behavioral assumptions namely(More)