Michał Kaszuba

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Detection of mutations in families with a hereditary predisposition to colon cancer gives an opportunity to precisely define the high-risk group. 36 patients operated on for colon cancer, with familiar prevalence of this malignancy, were investigated using the DNA microarrays method with the potential detection of 170 mutations in MLH1, MSH2, MSH6, CHEK2,(More)
Colorectal cancer (CC), due to its frequency and social costs is a subject of extensive screening programs (colo-noscopy and new developments) in several countries, including Poland. Relatively common and defined genetic predispositions to different forms of CC make genetic screening an attractive alternative, not only in families with positive CC history.(More)
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