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  • Micah Holland, Hisato Yagi, +4 authors Royston Jefferis
  • Chemistry, Medicine
  • Biochimica et biophysica acta
  • 2006 (First Publication: 1 April 2006)
  • Post-translational modifications (PTMs) of proteins produced in vivo may be tissue, developmentally and/or disease specific. PTMs impact on the stability and function of proteins and offer aContinue Reading
  • Micah Holland, Peter Hewins, Margaret Goodall, D. Adu, Royston Jefferis, Caroline O. S. Savage
  • Biology, Medicine
  • Clinical and experimental immunology
  • 2004 (First Publication: 1 October 2004)
  • A characteristic feature of Wegener's granulomatosis is the presence of antineutrophil cytoplasm antibodies (ANCA) to proteinase 3 (PR3). In vitro, ANCA activate neutrophils by co-ligating PR3 andContinue Reading