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Inhibition of lipopolysaccharide-stimulated NO production by a novel synthetic compound CYL-4d in RAW 264.7 macrophages involving the blockade of MEK4/JNK/AP-1 pathway.
In the present study, a novel synthetic compound 4-(2-(cyclohex-2-enylidene)hydrazinyl)quinolin-2(1H)-one (CYL-4d) was found to inhibit lipopolysaccharide (LPS)-induced nitric oxide (NO) productionExpand
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Apoptosis contributes to the decrement in numbers of alveolar macrophages from rats with polymicrobial sepsis.
To investigate the effects of sepsis-related acute lung injury on the events of alveolar macrophages apoptosis and phagocytosis, cecal-ligated-and-punctured male Sprague-Dawley rats were employed asExpand
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Purification of Cu/Zn superoxide dismutase from Piper betle leaf and its characterization in the oral cavity.
The aim of this study was to purify protein(s) from Piper betle leaf for identification and further characterization. A functionally unknown protein was purified to apparent homogeneity with aExpand
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Supercritical fluids extraction of cinnamic acid derivatives from Brazilian propolis and the effect on growth inhibition of colon cancer cells
Abstract This work examined supercritical carbon dioxide (SC-CO 2 ) extractions of an anti-cancer compound, 3,5-diprenyl-4-hydroxycinnamic acid (DHCA) from propolis lumps and studied the inhibitiveExpand
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Supercritical fluids extraction of capillarisin from Artemisia capillaris and its inhibition of in vitro growth of hepatoma cells
Abstract This work studies the supercritical carbon dioxide (SC-CO2) extractions of capillarisin from Artemisia capillaris T. and the effect of the extracts on the growth inhibition of two humanExpand
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YC-1 induces G0/G1 phase arrest and mitochondria-dependent apoptosis in cisplatin-resistant human oral cancer CAR cells
Oral cancer is a serious and fatal disease. Cisplatin is the first line of chemotherapeutic agent for oral cancer therapy. However, the development of drug resistance and severe side effects causeExpand
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Selective induction of G2/M arrest and apoptosis in HL-60 by a potent anticancer agent, HMJ-38.
We previously reported that HMJ-38 was the most potent 2-phenyl-4-quinozolinone derivative in inhibiting tubulin polymerization and showed significant cytotoxicity against several human tumor cellExpand
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AKT serine/threonine protein kinase modulates baicalin-triggered autophagy in human bladder cancer T24 cells.
Baicalin is one of the major compounds in the traditional Chinese medicinal herb from Scutellaria baicalensis Georgi. We investigated the molecular mechanisms of cell autophagy induced by baicalin inExpand
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Synthesis and anticancer activity of benzyloxybenzaldehyde derivatives against HL-60 cells.
A series of benzyloxybenzaldehyde derivatives were prepared and tested against the HL-60 cell line for anticancer activity. Preliminary structure-activity relationships were established. It wasExpand
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Dang-Gui-Bu-Xai-Tang Modulated the Immunity of Tumor Bearing Mice
Dang-Gui-Bu-Xai-Tang (DGBXT), which includes Radix Angelicae Sinensis and Radix Astragali Membranaceus, is a traditional Chinese medicine used to modulate the lymphocyte activity of cancer patientsExpand
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