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OBJECTIVE Candidate gene association studies and genome-wide association studies (GWAs) have identified a large number of single nucleotide polymorphisms (SNPs) loci affecting susceptibility to rheumatoid arthritis (RA). However, for the same locus, some studies have yielded inconsistent results. To assess all the available evidence for association, we(More)
In this paper, a blind OFDM system parameters estimation method for software defined radio (SDR) is proposed. This method sequentially estimate the sampling frequency, the number of subcarriers, the CP length as well as the timing and frequency offset in OFDM systems. The blind estimation is based on a combination of the cyclostationarity test and(More)
PURPOSE Human papillomavirus (HPV) as a risk factor for esophageal squamous cell carcinoma (ESCC) has previously been studied, but importance of HPV status in ESCC for prognosis is less clear. METHODS A total of 105 specimens with ESCC were tested by in situ hybridization for HPV 16/18 and immunohistochemistry for p16 expression. The 5-year overall(More)
Timing and frequency offset estimation based on the second order cyclostationarity have been explored in many literatures [1][9]. In this article, we revisit the class of these estimators and propose for both single carrier and OFDM systems, a new method for timing and frequency offset estimation. Different from the previous methods, here, the estimation of(More)
Cyclostationarity is a significant feature of numerous physical and man-made processes. Specially in wireless communications, it has been explored and applied for many processing, like timing and frequency synchronization, channel estimation, and modulation classification. In this paper, we notice that the second order time varying auto-correlation of the(More)
Rheumatoid arthritis (RA) is an autoimmune disease that has a complex genetic basis. Therefore, it is important to explore the genetic background of RA. The extensive recent application of polymorphic genetic markers, especially single nucleotide polymorphisms, has presented us with a large quantity of genetic data. In this study, we developed the Database(More)
The initiation and development of rheumatoid arthritis (RA) is closely related to mutual dysfunction of multiple pathways. Furthermore, some similar molecular mechanisms are shared between RA and other immune diseases. Therefore it is vital to reveal the molecular mechanism of RA through searching for subpathways of immune diseases and investigating the(More)
Demographic events such as migration, and evolutionary events like mutation and recombination, have contributed to the genetic variations that are found in the human genome. During the evolution and differentiation of human populations, different functional genes and pathways (a group of genes that act together to perform specific biological tasks) would(More)