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We report the complete sequence of an extreme halophile, Halobacterium sp. NRC-1, harboring a dynamic 2,571,010-bp genome containing 91 insertion sequences representing 12 families and organized into a large chromosome and 2 related minichromosomes. The Halobacterium NRC-1 genome codes for 2,630 predicted proteins, 36% of which are unrelated to any(More)
—Sensor-enabled RFID technology has generated a lot of interest from industries lately. Integrated with miniaturized sensors, RFID tags could provide not only the IDs but also valuable real-time information about the state of the corresponding objects or the surrounding environment, which is beneficial to many practical applications, such as warehouse(More)
—Microeconomics-inspired spectrum auctions can dramatically improve the spectrum utilization for wireless networks to satisfy the ever increasing service demands. However, the back-room dealing (i.e., the frauds of the insincere auctioneer and the bid-rigging between the greedy bidders and the auctioneer) poses significant security challenges, and fails all(More)
PCNA (proliferating-cell nuclear antigen) is a ring-shaped protein that encircles duplex DNA and plays an essential role in many DNA metabolic processes. The PCNA protein interacts with a large number of cellular factors and modulates their enzymatic activities. In the present paper, we summarize the structures, functions and interactions of the archaeal(More)
The ESX-1 secretion system plays a critical role in the virulence of M. tuberculosis and M. marinum, but the precise molecular and cellular mechanisms are not clearly defined. Virulent M. marinum is able to escape from the Mycobacterium-containing vacuole (MCV) into the host cell cytosol, polymerize actin, and spread from cell to cell. In this study, we(More)
Chromosomal DNA replication requires the spatial and temporal coordination of the activities of several complexes that constitute the replisome. A previously uncharacterized protein, encoded by TK1252 in the archaeon Thermococcus kodakaraensis, was shown to stably interact with the archaeal GINS complex in vivo, a central component of the archaeal(More)
Proliferating cell nuclear antigen (PCNA) is a ring-shaped protein that encircles duplex DNA and plays an essential role in many DNA metabolic processes in archaea and eukarya. The eukaryotic and euryarchaea genomes contain a single gene encoding for PCNA. Interestingly, the genome of the euryarchaeon Thermococcus kodakaraensis contains two PCNA-encoding(More)
Proliferating cell nuclear antigen (PCNA) monomers assemble to form a ring-shaped clamp complex that encircles duplex DNA. PCNA binding to other proteins tethers them to the DNA providing contacts and interactions for many other enzymes essential for DNA metabolic processes. Most eukarya and euryarchaea have only one PCNA homolog but Thermococcus(More)
The essential impediment to apply cognitive radio (eR) technology for spectrum utilization improvement lies in the uncertainty of licensed spectrum supply. In this paper, we investigate the joint routing and link scheduling problem of multi­ hop eR networks under uncertain spectrum supply. We model the vacancy of licensed bands with a series of random(More)