Mi-Young Shin

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  • E. Yücesan, C.-H. Chen, J. L. Snowdon, Miyoung Shin, Robert G. Sargent, Amrit L. Goel
  • 2002
This paper presents a novel approach for developing simulation metamodels using Gaussian radial basis functions. This approach is based on some recently developed mathematical results for radial basis functions. It is systematic, explicitly controls the underfitting and overfitting tradeoff, and uses a fast computational algorithm that requires minimal(More)
In practice, some drugs produce a number of negative biological effects that can mitigate their effectiveness as a remedy. To address this issue, several studies have been performed for the prediction of drug-induced toxicity from gene-expression data, and a significant amount of work has been done on predicting limited drug-induced symptoms or single-organ(More)
The expression of epidermal growth factor receptor (EGFR) is an important diagnostic marker for triple-negative breast cancer (TNBC) cells, which lack three hormonal receptors: estrogen and progesterone receptors as well as epidermal growth factor receptor 2. EGFR transactivation can cause drug resistance in many cancers including TNBC, but the mechanism(More)
OBJECTIVE To evaluate the usefulness of transvaginal ultrasound measurements of cervical length before and after elective prophylactic cervical cerclage in predicting preterm delivery before 32 weeks of gestation. METHODS Women who underwent an elective cerclage operation at 14 to 19 weeks of gestation and who delivered between January 2004 and December(More)
Cytarabine is the primary chemotherapeutic agent used for treatment of acute myeloid leukemia (AML). Disease relapse after initial remission remains one of the most pressing therapeutic challenges in the treatment of AML. Relapsed disease is often resistant to cytarabine and subsequent salvage therapy is ineffective. Recent studies have shown that some(More)
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