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BACKGROUND AND PURPOSE Virtual reality (VR) is a new promising computer-assisted technology to promote motor recovery in stroke patients. VR-induced neuroplasticity supporting locomotor recovery is not known. We investigated the effects of VR intervention on cortical reorganization and associated locomotor recovery in stroke patients. METHODS Ten chronic(More)
OBJECTIVES We attempted to evaluate whether cortical activation resulting from hand movements is changed by transcranial direct current stimulation (tDCS) applied on the primary motor cortex for the hand in the human brain, using functional MRI (fMRI). METHODS Fourteen normal subjects were recruited; subjects were randomly assigned to either the tDCS(More)
OBJECTIVES Somatotopic arrangements of the corticospinal tract (CST) in the human brain have been generally elucidated; however, very little is known about the somatotopy at the medullary pyramid (MP). Using diffusion tensor tractography (DTT), we investigated the somatotopic arrangement of the CST at the MP in the normal human brain. METHODS We recruited(More)
OBJECTIVE Adipocyte fatty acid-binding protein (A-FABP) is a major cytoplasmic protein in adipocytes and macrophages and is closely associated with metabolic syndrome, type 2 diabetes, and atherosclerosis. Here, we investigated whether A-FABP was associated with nonalcoholic fatty liver disease (NAFLD) in type 2 diabetes. RESEARCH DESIGN AND METHODS We(More)
BACKGROUND Recently, the measurement of glycated hemoglobin (HbA1c) was recommended as an alternative to fasting plasma glucose or oral glucose tolerance tests for diagnosing diabetes mellitus (DM). In this study, we analyzed HbA1c levels for diabetes mellitus screening in a Korean rural population. METHODS We analyzed data from 10,111 subjects from a(More)
In most cases authors are permitted to post their version of the article (e.g. in Word or Tex form) to their personal website or institutional repository. Authors requiring further information regarding Elsevier's archiving and manuscript policies are encouraged to visit: Keywords: Iterative methods Order of convergence Rational maps Basin of attraction(More)
Active execution, proprioception, and touch discrimination are important for the execution of movement. In the current study, we attempted to compare the cortical activation patterns of active exercise, proprioceptive input, and touch stimulation in the normal human brain using functional MRI. Nine subjects were recruited for this study. Functional MRI was(More)
Little is known about the recovery mechanism of somatosensory function in thalamic hemorrhage. We investigated the recovery mechanism of somatosensory function, using functional MRI (fMRI) findings by proprioceptive input in chronic patients with thalamic hemorrhage. Eleven consecutive chronic patients with thalamic hemorrhage who showed severe(More)
PURPOSE We hypothesized that diffusion tensor imaging (DTI) could be useful for exploring corticospinal tract (CST) regeneration if longitudinal changes of diffusion anisotropy can be detected. In this study, we explored the recovery of a CST partially damaged by intracerebral hematoma in a patient by DTI. METHODS A 61-year-old female patient and six(More)
PURPOSE Recovery mechanisms supporting upper extremity motor recovery following stroke are well established, but cortical mechanism associated with lower extremity motor recovery is unknown. The aim of this study was to assess cortical reorganization associated with lower extremity motor recovery in a hemiparetic patient. METHODS Six control subjects and(More)