Mi Yeung Sohn

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BACKGROUND Although many methods have been developed to treat ear keloids, new therapeutic options are still needed. OBJECTIVE To determine the effects of topical mitomycin C (MC) on shave-removed wounds and fibroblasts of ear keloids. METHODS Fourteen ear keloids in 12 patients were shaved, and MC (1 mg/mL) was applied to the resected bed for 5(More)
Amniotic fluid-derived stem cells (AFSCs) are a potential cell source for therapeutic applications. They can be easily mass produced, cryopreserved and shipped to clinics for immediate use. However, one major obstacle to the manufacturing of clinical grade stem cells is the need for current good manufacturing practices for cryopreservation, storage, and(More)
Antimicrobial peptides (AMPs) have been widely accepted as major contributors to cutaneous innate non-specific immunity, which is the first line of defense against invading pathogens. Altered expression of AMPs has been described in chronic inflammatory disorders of the skin. This study was conducted to clarify the expression of AMPs, including psoriasin,(More)
BACKGROUND Although photodynamic therapy (PDT) is widely performed for acne, little is known about its exact therapeutic mechanism. OBJECTIVE We aimed to estimate the efficacy and safety of PDT on acne and to discover its mode of action. METHODS We performed PDT on 12 patients with mild to moderate acne. The clinical efficacy was assessed by counting(More)
Sebaceous gland hyperplasia and increased sebum secretion after irradiation of ultraviolet (UV)-B has been widely accepted. This study was performed to clarify expression of inflammatory cytokines after irradiating UV-B in cultured sebocytes. Reverse transcription polymerase chain reaction was performed to measure gene expression of inflammatory cytokines,(More)
BACKGROUND Inflammatory cytokines are the key factor in the pathophysiology of acne. It is well known that keratinocytes synthesize many kinds of inflammatory cytokines. In addition, it is reported that inflammatory cytokines are also expressed from sebocytes, which originate from the same stem cells with keratinocytes. AIM To clarify changes in the(More)
BACKGROUND Acne vulgaris has been linked to the Western diet. Hyperglycemic diet increases insulin and insulin-like growth factor (IGF)-1. Deeper insights into IGF-1-mediated signal pathway are critical importance to understand the impact of Western diet. OBJECTIVE We investigated the effect of IGF-1 on the expression of inflammatory biomarkers and sebum(More)
Vol. 28, No. 5, 2016 665 Received July 15, 2015, Revised September 25, 2015, Accepted for publication October 5, 2015 Corresponding author: Weon Ju Lee, Department of Dermatology, Kyungpook National University Hospital, 130 Dongdeok-ro, Jung-gu, Daegu 41944, Korea. Tel: 82-53-420-5838, Fax: 82-53-426-0770, E-mail: weonju@knu.ac.kr This is an Open Access(More)
Vol. 28, No. 1, 2016 129 Received February 5, 2015, Revised March 21, 2015, Accepted for publication March 30, 2015 Corresponding author: Weon Ju Lee, Department of Dermatology, Kyungpook National University School of Medicine, 130 Dongdeok-ro, Jung-gu, Daegu 41944, Korea. Tel: 82-53-420-5838, Fax: 82-53-426-0770, E-mail: weonju@knu.ac.kr This is an Open(More)
352 Ann Dermatol Received March 2, 2016, Revised May 30, 2016, Accepted for publication June 2, 2016 Corresponding author: Weon Ju Lee, Department of Dermatology, Kyungpook National University Hospital, 130 Dongdeok-ro, Jung-gu, Daegu 41944, Korea. Tel: 82-53-420-5838, Fax: 82-53-426-0770, E-mail: weonju@knu.ac.kr This is an Open Access article distributed(More)