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Advances in neuroscience have enabled researchers to develop computational models of auditory, visual and learning perceptions in the human brain. HMAX, which is a biologically inspired model of the visual cortex, has been shown to outperform standard computer vision approaches for multi-class object recognition. HMAX, while computationally demanding, can(More)
The subchronic toxicity of Aristolochiae fructus containing aristolochic acids (AAs), a natural component in the Aristolochiaceae family, was investigated. The A. fructus was daily administered by gavage to male and female rats for 90 d at dose levels of 21.35, 213.5, and 2135 mg/kg (equivalent to 0.05, 0.5, and 5 mg/kg as AAs, respectively). During the(More)
In this study, we identified p53 as a novel TCTP-interacting protein using TCTP as bait. Also, we determined the critical binding sites between TCTP and p53. To elucidate the functional consequence of the interaction, we developed the overexpression and inhibition system of TCTP and p53 expression. Overexpression of TCTP in lung carcinoma cells reversed p53(More)
Salmonella enterica serovar Typhimurium DT104 (Salmonella Typhimurium DT104 or DT104) has been emerging as a common pathogen for human in Korea since 1997. In order to compare the genomic relationship and to search for the dominant strains in Korea, we conducted pulsed-field gel electrophoresis (PFGE) and IS200 fingerprinting of 25 epidemiological unrelated(More)
Because of the diversity in human papillomavirus (HPV) distribution, according to the population and region, detailed investigations of HPV genotypes are important in designing more effective HPV vaccines for any given country. HPV DNA oligonucleotide microarray was used to investigate the distribution of HPV genotypes among commercial sex workers. The(More)
OBJECTIVE The role of incretins in type 2 diabetes is controversial. This study investigated the association between incretin levels in obese Korean children and adolescents newly diagnosed with type 2 diabetes. DESIGN We performed a 2-hr oral glucose tolerance test (OGTT) in obese children and adolescents with type 2 diabetes and with normal glucose(More)
In this study, we determined whether p53 expression affected the sensitivity of non-small cell lung cancer (NSCLC) and colon cancer cells to bleomycin (BLM). Two human NSCLC cell lines (A549 expressing wild-type p53 and p53-null H1299) and two colon cancer cell lines (HCT116 p53+/+ and its p53 deficient subline HCT116 p53-/-) were subjected to treatment(More)
Video and image content has begun to play a growing role in many applications, ranging from video games to autonomous self-driving vehicles. In this paper, we present accelerators for gist-based scene recognition, saliency-based attention, and HMAX-based object recognition that have multiple uses and are based on the current understanding of the vision(More)
Doxazosin, a commonly prescribed treatment for patients with benign prostatic hyperplasia, serves as an α1-blocker of the adrenergic receptors. In this study, we calculated its effect on the ovarian carcinoma cells. Doxazosin induces dose-dependent growth suppression and is additively activated through IFN-α or IFN-γ stimulation. They both enhanced G1 phase(More)
Mayenite-based oxides [12CaO·7Al2O3] starting from [Ca24Al28O64] 4+ + 2O2− (insulator) and subsequently annealed so as to obtain [Ca24Al28O64] 4+ + 4e− (metal) were studied by reflectance and transmission on seven samples with dc conductivities spanning the range 10−10 to 1500 Ω−1 cm−1. Three of them are essentially insulating. The remaining display an(More)