Mette Møller Nielsen

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PURPOSE Few studies have examined the possible importance of biologic prognostic factors in breast cancer connected with differentiation and growth in predicting response to a specific adjuvant treatment. HER2, epidermal growth factor receptor (EGFR), and p53 have all been suggested as possible markers of tamoxifen resistance. The aim of this study was to(More)
The potential of liquid manure as sole nutrient source for cultivation of Ulva lactuca was investigated with the perspective of utilizing the produced biomass for feed and/or energy. Algae grown with manure demonstrated equal growth rates to algae grown with standard f/2-medium. The optimum manure concentration, expressed as ammonium concentration, was 25(More)
In this study, we present a new objective method for measuring the eye colour on a continuous scale that allows researchers to associate genetic markers with different shades of eye colour. With the use of the custom designed software Digital Iris Analysis Tool (DIAT), the iris was automatically identified and extracted from high resolution digital images.(More)
Beta-sheet proteins are particularly resistant to denaturation by sodium dodecyl sulfate (SDS). Here we compare unfolding of two beta-sandwich proteins TNfn3 and TII27 in SDS. The two proteins show different surface electrostatic potential. Correspondingly, TII27 unfolds below the critical micelle concentration via the formation of hemimicelles on the(More)
INTRODUCTION This study was conducted to establish the maximum tolerated dose (MTD) of intravenous vinorelbine and on the determined dose to assess efficacy and safety in patients with metastatic breast cancer previously treated with epirubicin. PATIENTS AND METHODS Patients had histologically proven breast cancer and had received a prior epirubicin based(More)
In the Danish Wadden Sea the intertidal distribution of the introduced bivalve Ensis americanus (syn. E. directus) is restricted to a narrow zone around the mean low water level. To test the possible impact of birds and submersion time on dynamics and distribution of the clams, adult specimens of E. americanus collected near the low water line were(More)
This paper describes the procedure of changing from 2D to 3D treatment planning guidelines for post-mastectomy radiotherapy in Denmark. The aim of introducing 3D planning for post-mastectomy radiotherapy was to optimize the target coverage and minimize the dose to the normal tissues. Initially, it was investigated whether it was possible to find a treatment(More)
Zusammenfassung Die Indikation für adjuvante Postmastektomie-Radiotherapie (PMRT) bei Brustkrebspatienten mit kleinen Tumoren und 1–3 Makrometastasen in der Axilla wird trotz entsprechender Empfehlungen in der jüngsten Auswertung der Early Breast Cancer Trialists‘ Collaborative Group noch immer kontrovers diskutiert. In der vorliegenden Übersichtsarbeit(More)
Around Denmark, Laminaria digitata and Saccharina latissima are particularly common macroalgae species and are considered as prospective candidates for biorefineries. In this study, the carbohydrate composition and protein levels of L. digitata and S. latissima from three different sites in Denmark were compared for 1 year, and compositional variations of(More)
Cultivation of Laminariales is an expanding industry and intensive investigations have been conducted in order to optimize the entire production chain from spore to sporophyte. However, despite intense research within the field, literature on the very early development of kelp microstages is scarce. In that perspective, the aim of the present study was to(More)