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The xenobiotic transporters, Multidrug Resistance 1 (MDR1/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2) may restrict intestinal absorption of various carcinogens, including heterocyclic(More)
Background: Genetic variation that modifies the gut barrier function or the inflammatory response may modify the risk of colorectal cancer (CRC). The intestinal xenobiotic transporters, Multidrug(More)
Medical Department, and Clinical Biochemical Department, Viborg Regional Hospital, DK-8800 Viborg, Danish Cancer Society, Institute of Cancer Epidemiology, DK-2100 Copenhagen Department of Clinical(More)
Smoking, dietary factors, and alcohol consumption are known life style factors contributing to gastrointestinal carcinogenesis. Genetic variations in carcinogen handling may affect cancer risk. The(More)
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