Merja M Roivainen

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Molecular and biological characteristics of echovirus 22, a representative of a new picornavirus group.

Glyn Stanway, Nisse Kalkkinen, +5 authors Timo Hyypiä
Journal of virology
1994

Recent sequence analysis revealed that the human pathogen echovirus 22 (EV22) is genetically distant from all the other picornaviruses studied to date (T. Hyypiä, C. Horsnell, M. Maaronen, M. Khan,… (More)

Etiology of community-acquired pneumonia in 254 hospitalized children.

Taina Juvén, Jussi A Mertsola, +6 authors Olli Ruuskanen
The Pediatric infectious disease journal
2000

BACKGROUND Childhood community-acquired pneumonia is a common illness, but there have been relatively few comprehensive studies of the viral and bacterial etiology in developed countries. The aim of… (More)

Entry of coxsackievirus A9 into host cells: specific interactions with alpha v beta 3 integrin, the vitronectin receptor.

Merja M Roivainen, Laura Piirainen, +4 authors Timo Hyypiä
Virology
1994

Attachment and entry of coxsackievirus A9 (CAV-9) to GMK cells were previously shown to be dependent on an arginine-glycine-aspartic acid (RGD) motif in the capsid protein VP1, suggesting integrins… (More)

Enterovirus surveillance reveals proposed new serotypes and provides new insight into enterovirus 5'-untranslated region evolution.

Teemu P Smura, Soile Blomqvist, +6 authors Merja M Roivainen
The Journal of general virology
2007

Human enteroviruses are currently grouped into five species Human enterovirus A (HEV-A), HEV-B, HEV-C, HEV-D and Poliovirus. During surveillance for enteroviruses serologically non-typable… (More)

A prospective study of the role of coxsackie B and other enterovirus infections in the pathogenesis of IDDM. Childhood Diabetes in Finland (DiMe) Study Group.

Heikki Hyöty, Mikko Hiltunen, +7 authors Tapani Hovi
Diabetes
1995

Coxsackievirus B infections have been associated with clinical manifestation of insulin-dependent diabetes mellitus (IDDM) in several studies, but their initiating role in the slowly progressing… (More)

Global profiling of coxsackievirus- and cytokine-induced gene expression in human pancreatic islets

Petri Ylipaasto, Burak Kutlu, +9 authors Merja M Roivainen
Diabetologia
2005

It is thought that enterovirus infections initiate or facilitate the pathogenetic processes leading to type 1 diabetes. Exposure of cultured human islets to cytolytic enterovirus strains kills beta… (More)

Evolutionary dynamics and temporal/geographical correlates of recombination in the human enterovirus echovirus types 9, 11, and 30.

E. Carol McWilliam Leitch, María Cabrerizo, +11 authors Peter Simmonds
Journal of virology
2010

The relationship between virus evolution and recombination in species B human enteroviruses was investigated through large-scale genetic analysis of echovirus type 9 (E9) and E11 isolates (n = 85 and… (More)

Antibodies to the vitronectin receptor (integrin alpha V beta 3) inhibit binding and infection of foot-and-mouth disease virus to cultured cells.

Analía Berinstein, Merja M Roivainen, Tapani Hovi, Peter W. Mason, Barry Baxt
Journal of virology
1995

The amino acid sequence Arg-Gly-Asp (RGD) is highly conserved on the VP1 proteins of different serotypes and subtypes of foot-and-mouth disease virus (FMDV) and is essential for cell attachment. This… (More)

Saffold Virus, a Human Theiler's-Like Cardiovirus, Is Ubiquitous and Causes Infection Early in Life

Jan Zoll, Sandra Erkens Hulshof, +6 authors Frank J. M. van Kuppeveld
PLoS pathogens
2009

The family Picornaviridae contains well-known human pathogens (e.g., poliovirus, coxsackievirus, rhinovirus, and parechovirus). In addition, this family contains a number of viruses that infect… (More)

The minor receptor group of human rhinovirus (HRV) includes HRV23 and HRV25, but the presence of a lysine in the VP1 HI loop is not sufficient for receptor binding.

Marketa Vlasak, Merja M Roivainen, +5 authors Dieter Blaas
Journal of virology
2005

Like all 10 minor receptor group human rhinoviruses (HRVs), HRV23 and HRV25, previously classified as major group viruses, are neutralized by maltose binding protein (MBP)-V33333 (a soluble… (More)

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