Claim Your Author Page
Ensure your research is discoverable on Semantic Scholar. Claiming your author page allows you to personalize the information displayed and manage publications (all current information on this profile has been aggregated automatically from publisher and metadata sources).
Intermittent intense ultraviolet (UV) exposure represents an important aetiological factor in the development of malignant melanoma. The ability of UV radiation to cause tumour-initiating DNA… Continue Reading
Adoptive cell transfer therapies (ACTs) with cytotoxic T cells that target melanocytic antigens can achieve remissions in patients with metastatic melanomas, but tumours frequently relapse.… Continue Reading
&NA; Inhibitors of the receptor tyrosine kinase c‐MET are currently used in the clinic to target oncogenic signaling in tumor cells. We found that concomitant c‐MET inhibition promoted adoptive T… Continue Reading
Human melanomas exhibit considerable genetic, pathologic, and microenvironmental heterogeneity. Genetically engineered mice have successfully been used to model the genomic aberrations contributing… Continue Reading
Melanoma patients resistant to RAF/MEK-inhibitors (RMi) are frequently resistant to other therapies, such as immune checkpoint inhibitors (ICI), and individuals succumb to their disease. New drugs… Continue Reading
Human melanomas exhibit considerable genetic, pathological, and microenvironmental heterogeneity. Genetically engineered mice have successfully been used to model the genomic aberrations contributing… Continue Reading