Meredith Farmer

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Dense-core granules (DCGs) are organelles found in specialized secretory cells, including neuroendocrine cells and neurons. Neuronal DCGs facilitate many critical processes, including the transport and secretion of proteins involved in learning, and yet their transport and exocytosis are poorly understood. We have used wide-field and total internal(More)
Human platelet factor 4, a protein that binds heparin, has been purified to apparent homogeneity and the complete amino acid sequence of the protein has been determined. The 70-residue polypeptide chain contains no methionine, tryptophan, or phenylalanine, and contains only a single tyrosyl residue. The sequence analysis demonstrates a highly negatively(More)
Diaspirin crosslinked hemoglobin (DCLHb), a hemoglobin based oxygen carrying solution prepared from outdated human blood, is subjected to a heat treatment step to inactivate viruses in our manufacturing process. To validate the efficacy of this inactivation, we have simulated the heat treatment procedure at a reduced scale using hemoglobin solution spiked(More)
A sensitive assay using inductively coupled plasma atomic emission spectroscopy (ICP-AES) has been applied to the measurement of trace elements in diaspirin cross-linked hemoglobin (DCLHb) solutions. Calcium, magnesium, zinc and iron were the only elements detected at greater than background levels. Ag, Al, As, B, Ba, Bi, Cd, Co, Cr, Cu, Mn, Mo, Pb, Sb, Se,(More)
We have investigated the electrical properties of the hetero structures deposited on conductive glass. The hetero structures made with type II CdTe quantum dots present interesting peculiarities. Low frequency (20Hz ≤ f≤ 200kHz; f= 8804) dielectric properties of type II CdTe, type II CdTe blended with Single-wall carbon nano tubes SWNTs functionalized with(More)
A study has been made to investigate the detection sensitivity of Borate Glass for the heavily ionizing fission fragment tracks. The latent damage tracks produced by fission fragments in Borate Glass, with and without Aluminium Oxide as an additive, have been studied under a high resolution scanning electron microscope. Tracks have been found and studied(More)
The rotational strengths of the four longer wavelength transitions, B(2u), B(1u), and the two E(1u), of adenosine derivatives constrained in the syn form have been investigated theoretically and experimentally. The theory combines a complete neglect of differential overlap version S (CNDO/S) description of the base with a generalized bond exciton method by(More)
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