Meredith Brown

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A central issue in speech intonation research concerns how fundamental frequency (f0) variation relates to phonological categories. The hypothesis was tested that pitch range variation which affects whether one syllable is higher or lower than another would elicit categorical shifts in f0 extremum timing in an imitation task. Participants heard synthetic(More)
Earlier studies showed that two protein components, P(I) and P(II), are concerned with the adenylylation and deadenylylation of Escherichia coli glutamine synthetase (EC 6.3.1.2). P(I) by itself catalyzes both adenylylation and deadenylylation, but its activity is modulated by the P(II)-protein and by glutamine, 2-oxoglutarate, ATP, and UTP, The(More)
Previous work examining prosodic cues in online spoken-word recognition has focused primarily on local cues to word identity. However, recent studies have suggested that utterance-level prosodic patterns can also influence the interpretation of subsequent sequences of lexically ambiguous syllables (Dilley, Mattys, & Vinke, Journal of Memory and Language,(More)
Mixed lineage kinase (MLK) 4, or MLK4, is a member of the MLK family of mitogen-activated protein kinase kinase kinases (MAP3Ks). Typically, MAP3Ks function to activate the mitogen-activated protein kinase (MAPK)-signaling pathways and regulate different cellular responses. However, here we report that MLK4β, unlike the other MLKs, negatively regulates the(More)
0749-596X/$ see front matter 2011 Elsevier Inc doi:10.1016/j.jml.2011.08.006 ⇑ Corresponding author. Address: University of Ro Box 270268, Rochester, NY 14627-0268, USA. Fax: + E-mail address: mbrown@alum.mit.edu (M. Brow Although sentences are thought to be generally easier to process when given information precedes new information, closer examination(More)
Alternative processing of α-thyroid hormone receptor (TRα, NR1A1) mRNAs gives rise to two functionally antagonistic nuclear receptors: TRα1, the α-type receptor, and TRα2, a non-hormone binding variant that is found only in mammals. TRα2 shares an unusual antisense coding overlap with mRNA for Rev-erbα (NR1D1), another nuclear receptor protein. In this(More)
Problem gambling is a significant mental health problem that creates a multitude of intrapersonal, interpersonal, and social difficulties. Recent empirical evidence suggests that personality disorders, and in particular borderline personality disorder (BPD), are commonly co-morbid with problem gambling. Despite this finding there has been very little(More)
There is an emerging literature on visual search in natural tasks suggesting that task-relevant goals account for a remarkably high proportion of saccades, including anticipatory eye movements. Moreover, factors such as "visual saliency" that otherwise affect fixations become less important when they are bound to objects that are not relevant to the task at(More)