Mercedes Rodriguez

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Chagas disease is endemic to Latin America, but human migration is extending its distribution. This report describes the parasitological and serological course of disease in a Spanish patient fatally infected via a blood product transfusion, as well as the monitoring of the donor. Before undergoing immunosuppression, multitransfused patients should be(More)
BACKGROUND The 65-kD isoform of glutamic acid decarboxylase (GAD65) is a major autoantigen in type 1 diabetes. We hypothesized that alum-formulated GAD65 (GAD-alum) can preserve beta-cell function in patients with recent-onset type 1 diabetes. METHODS We studied 334 patients, 10 to 20 years of age, with type 1 diabetes, fasting C-peptide levels of more(More)
BACKGROUND Suicide and suicidal behaviour are multifaceted events requiring complex solutions. Controlling the environment is a neglected solution, despite strong support for this approach from the World Health Organization (WHO). METHOD To discuss this approach from a global view, this review is written by authors from various cultures: American,(More)
BACKGROUND & AIMS The natural course after hepatitis B surface antigen (HBsAg) seroclearance in Caucasian patients with chronic hepatitis B virus (HBV) infection is not well-defined. To investigate the clinical characteristics and outcome in a series of European Caucasian patients with chronic HBV infection according to HBsAg response over time. METHODS A(More)
Titanium and its alloys are widely used as implant materials for dental and orthopaedic applications. To improve their wear and corrosion resistance, several surface modifications that give rise to an outer ceramic layer of rutile have been developed. It is expected that after a long period of functional loading, rutile debris will arise from these modified(More)
The early diagnosis of congenital Chagas' disease is very important if infected newborns, whether symptomatic or not, are to receive adequate treatment. This paper describes the complications arising in the diagnosis of a newborn with fatal congenital Chagas' disease in Spain, a non-endemic area where visceral leishmaniasis is present.
A cDNA encoding for a predicted small heat shock protein (sHSP), Tsol-sfISP35.6, has been isolated by antibody screening of a Taenia solium c-DNA library. The clone was a full-length sequence (1172 bp) with an open reading frame of 945 bp and encoded for a 314 amino acid protein with deduced molecular mass of 35.6 kDa, isoelectric point of 5.6 arid the(More)
OBJECTIVE Schizophrenia is a devastating and common psychiatric disorder which is associated with a high degree of medical morbidity and reduced life span in addition to psychosis. In this article, these problems will be discussed in the context of schizophrenia and aging. METHOD The recent literature was reviewed using Pubmed, Medline, and Google scholar(More)