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Zebra mussel populations in Ebro and Mijares Rivers (northern Spain) were analyzed to study the mechanisms by which this aquatic species deals with pollution. Variability analyses of mitochondrial cytochrome oxidase I gene and of one nuclear microsatellite were performed for ten populations from the Ebro River and one from the Mijares River. Comparison of(More)
Cytochrome P450 aromatase is the enzyme complex responsible for the synthesis of estrogens by the aromatization of androgens. In the vast majority of tetrapods examined so far, aromatase is the product of the Cyp19 gene, which exists as a single copy per haploid genome. In contrast, in teleosts there are two isoforms of the aromatase gene, Cyp19a and(More)
The Royal Institute Elcano † (Real Instituto Elcano) in Spain is a prestigious independent political institute whose mission is to comment on the political situation in the world focusing on its relation to Spain. As part of its dissemination strategy it operates a public website. The online content can be accessed by navigating through categories or by a(More)
Vasa is a protein expressed mainly in germ cells and conserved across taxa. However, sex-related differences and environmental influences on vasa expression have not been documented. This study characterized the cDNA of a vasa homolog in the European sea bass, Dicentrarchuslabrax (sb-vasa), a gonochoristic fish with temperature influences on gonadogenesis.(More)
The present study addresses the role of aromatase and estrogen receptors in sex differentiation and development. With this purpose, a sea bass female- and a male-dominant group were obtained by successive size gradings since in this species females are already larger than males at the time of sex differentiation. Changes in cyp19a and cyp19b gene expression(More)
The pharmaceutical fluoxetine, a selective serotonin reuptake inhibitor (SSRI), is often detected in municipal wastewater treatment plant effluents and surface waters within the ng/l range. There is, however, insufficient research evaluating potential hazards of fluoxetine in aquatic organisms at environmentally relevant concentrations. Taking into account(More)
The teleost brain is characterized by exceptionally high levels of aromatase, the enzyme that converts androgens into estrogens, and by its continuous growth throughout life. Gonadal estrogens have been implicated in sex differentiation and the control of reproduction in adult fish, but the role of neural estrogens during early development is far from(More)
Androgens play key roles in vertebrate sex differentiation, gonadal maturation and reproductive behaviour and their actions are generally mediated through specific nuclear receptors. The present study describes the isolation, sequencing and characterization of the cDNA encoding the androgen receptor (AR) in the European sea bass. AR was cloned from a sea(More)
The European sea bass (Dicentrarchus labrax L.) is a differentiated gonochoristic marine teleost of the family Moronidae (closely related to the hermaphrodites of the family Serranidae), where many juvenile males exhibit intratesticular oocytes, suggesting a certain sexual lability. Like most fish, the sea bass does not have recognizable heterochromosomes(More)