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  • Keyun Qing, Jonathan Hansen, Kirsten A. Weigel-Kelley, Mengqun Tan, Shangzhen Zhou, Arun Srivastava
  • Medicine, Biology
  • Journal of virology
  • 2001 (First Publication: 1 October 2001)
  • Although adeno-associated virus type 2 (AAV) has gained attention as a potentially useful vector for human gene therapy, the transduction efficiencies of AAV vectors vary greatly in different cellsContinue Reading
  • Keyun Qing, Weiming Li, +6 authors Arun Srivastava
  • Biology, Medicine
  • Journal of virology
  • 2003 (First Publication: 15 February 2003)
  • The use of adeno-associated virus type 2 (AAV) vectors has gained attention as a potentially useful alternative to the more commonly used retrovirus and adenovirus vectors for human gene therapy.Continue Reading
  • Li Zhong, Keyun Qing, Yue Cindy Si, Linyuan Chen, Mengqun Tan, Arun Srivastava
  • Medicine, Biology
  • Journal of Biological Chemistry
  • 2004 (First Publication: 26 March 2004)
  • Recombinant adeno-associated virus 2 (AAV) vectors transduction efficiency varies greatly in different cell types. We have described that a cellular protein, FKBP52, in its phosphorylated formContinue Reading
  • Liujiang Song, Xiaomiao Li, +9 authors Arun Srivastava
  • Medicine, Biology
  • PloS one
  • 2013 (First Publication: 14 March 2013)
  • We have observed that of the 10 AAV serotypes, AAV6 is the most efficient in transducing primary human hematopoietic stem cells (HSCs), and that the transduction efficiency can be further increasedContinue Reading
  • Chen Ling, Kanit Bhukhai, +5 authors Arun Srivastava
  • Biology, Medicine
  • Scientific reports
  • 2016 (First Publication: 19 October 2016)
  • We have reported that of the 10 commonly used AAV serotype vectors, AAV6 is the most efficient in transducing primary human hematopoietic stem/progenitor cells (HSPCs). However, the transductionContinue Reading
  • Li Zhong, Weiming Li, +14 authors Arun Srivastava
  • Biology, Medicine
  • Human gene therapy
  • 2004 (First Publication: 1 December 2004)
  • Controversies abound concerning hematopoietic stem cell transduction by recombinant adeno-associated virus 2 (AAV) vectors. For human hematopoietic cells, we have shown that this problem is relatedContinue Reading
  • Mengqun Tan, Keyun Qing, Shangzhen Zhou, Mervin C. Yoder, Arun Srivastava
  • Biology
  • 2001 (First Publication: 1 June 2001)
  • Abstract Adeno-associated virus 2 (AAV), a nonpathogenic human parvovirus, has gained attention as a potentially useful vector for human gene therapy. Here, we report successful AAV-mediated stableContinue Reading