• Publications
  • Influence
Where does the toxicity of metal oxide nanoparticles come from: The nanoparticles, the ions, or a combination of both?
  • D. Wang, Z. Lin, +4 authors W. Lu
  • Medicine, Chemistry
  • Journal of hazardous materials
  • 5 May 2016
The toxicity of metal oxide nanoparticles (NPs) has aroused great concern over the past few years. However, there still remains the question whether the toxicity of the metal oxide NPs originatesExpand
  • 117
  • 3
Enhanced oral bioavailability of piperine by self-emulsifying drug delivery systems: in vitro, in vivo and in situ intestinal permeability studies
Abstract The main purpose of this work was to develop and evaluate a self-emulsifying drug delivery system (SEDDS) of piperine to enhance its solubility and bioavailability. The formulation wasExpand
  • 30
  • 3
Effects of Panax notoginseng Saponins on the Activities of CYP1A2, CYP2C9, CYP2D6 and CYP3A4 in Rats In Vivo
The aim of this study was to assess the influence of the Panax notoginseng saponins (PNS) on the activities of the drug‐metabolizing enzymes cytochrome P450 (CYP450) 1A2, 2 C9, 2D6 and 3A4 in rats.Expand
  • 15
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The mixture toxicity of environmental contaminants containing sulfonamides and other antibiotics in Escherichia coli: Differences in both the special target proteins of individual chemicals and their
Organisms in the environment are exposed to mixtures of multiple contaminants, leading to serious environmental harm. These mixtures pose an ecological risk and have attracted an increasing amount ofExpand
  • 17
  • 1
Time-dependent hormesis of chemical mixtures: A case study on sulfa antibiotics and a quorum-sensing inhibitor of Vibrio fischeri.
Sulfa antibiotics (SAs) and quorum-sensing inhibitor (QSI) may pose potential ecological risks because mixed using of them has been proposed to inhibit bacteria from generating antibiotic resistance.Expand
  • 18
Effects of safflower injection on the pharmacodynamics and pharmacokinetics of warfarin in rats
Abstract 1. Safflower injection (SI) is extracted from Chinese herbal medicine safflower that comprises many active components. Warfarin is a common anticoagulant and has exhibited drug interactionsExpand
  • 6
Effects of phillyrin and forsythoside A on rat cytochrome P450 activities in vivo and in vitro
Abstract 1. Phillyrin and forsythoside A are two important active ingredients in Forsythia suspensa. However, the effects of phillyrin and forsythoside A on the activities of cytochrome P450 (CYP450)Expand
  • 11
What are the differences between aerobic and anaerobic toxic effects of sulfonamides on Escherichia coli?
Bacteria in the environment face the threat of antibiotics. However, most studies investigating the toxicity and toxicity mechanisms of antibiotics have been conducted on microorganisms in aerobicExpand
  • 7
Similarities and differences in combined toxicity of sulfonamides and other antibiotics towards bacteria for environmental risk assessment
  • S. Fang, D. Wang, +4 authors Y. Liu
  • Medicine, Chemistry
  • Environmental Monitoring and Assessment
  • 22 June 2016
Antibiotics as a type of environmental contaminants are typically exposed to chemical mixtures over long periods of time, so chronic combined toxicity is the best way to perform an environmental riskExpand
  • 5
Quantitative Structure-Toxicity Relationship for Predicting Acute Toxicity of Phenols
Phenols represent one of the most important classes of environmental chemicals. Most of them may cause serious public health and environmental problems. The present work is to develop an effectiveExpand