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Characterization and elimination of artificial non-covalent light Chain dimers in reduced CE-SDS analysis of pertuzumab.
- L. Zhang, Mengdan Fei, +5 authors M. H. Xie
- Chemistry, Medicine
- Journal of pharmaceutical and biomedical analysis
- 9 August 2020
Capillary electrophoresis sodium dodecyl sulfate (CE-SDS), either in reduced (rCE-SDS) or non-reduced (nrCE-SDS) form, is widely used for purity evaluation and impurity analysis of monoclonal… Expand