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Continuous-flow microfluidics have evolved rapidly in the last decades, due to their advantages in effective and accurate control. However, complex control results in complicated valve actuations. As a result, sophisticated interactions between control and flow layers substantially raise the design difficulty. Previous work on design automation for(More)
In flow-based biochips, peristaltic pumps consisting of valves are essential to generate circulation flow in a mixer. When a peristaltic pump is activated, the related valves for peristalsis are required to be actuated for many times. However, the roles of valves in traditional chips are fixed, and therefore the valves for peristalsis can wear out much(More)
Microfluidic biochips are being used to perform ever more complex and error-prone bioassays. This results in increasing demand for design automation for such biochips, as these sophisticated designs are beyond the scope of manual design. So far, much research in the field of design automation has been devoted to satisfy this demand from biology, but the gap(More)
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