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Among image segmentation algorithms there are two major groups: (a) methods assuming known appearance models and (b) methods estimating appearance models jointly with segmentation. Typically, the first group optimizes appearance log-likelihoods in combination with some spacial regularization. This problem is relatively simple and many methods guarantee(More)
Modulation of urinary excretion of green tea polyphenols (GTPs) and oxidative DNA damage biomarker, 8-hydroxydeoxyguanosine (8-OHdG), were assessed in urine samples collected from a randomized, double-blinded and placebo-controlled phase IIa chemoprevention trial with GTP in 124 individuals. These individuals were sero-positive for both HBsAg and(More)
The log-likelihood energy term in popular model-fitting segmentation methods, e.g. [39, 8, 28, 10], is presented as a generalized "probabilistic K-means" energy [16] for color space clustering. This interpretation reveals some limitations, e.g. over-fitting. We propose an alternative approach to color clustering using kernel K-means energy with well-known(More)
To evaluate the efficacy of green tea polyphenols (GTPs) in modulating aflatoxin B(1) (AFB(1)) biomarkers, a total of 352 serum samples and 352 urine samples collected from a 3 month chemoprevention trial with 500 mg GTPs, 1000 mg GTPs and a placebo were measured for AFB(1)-albumin adducts (AFB-AA), aflatoxin M(1) (AFM(1)) and aflatoxin B(1)-mercapturic(More)
The increased application of carbon nanotubes (CNTs) has raised the level of public concern regarding possible toxicities. Using in vitro cellular assays, we were able to assess the immunotoxicity of pristine multi-wall carbon nanotubes (MWCNTs) and their derivatives, covalently functionalized with carboxyl (COOH) or polyethylene glycol (PEG), in rodent(More)
Numerous studies have demonstrated that damage of kidney of mice can be caused by exposure to titanium dioxide nanoparticles (TiO(2) NPs). However, the molecular mechanism of TiO(2) NPs-induced nephric injury remains unclear. In this study, the mechanism of nephric injury in mice induced by an intragastric administration of TiO(2) NPs was investigated. The(More)
This study evaluated the acute toxicity and biokinetics of intravenously administered silver nanoparticles (AgNPs) in mice. Mice were exposed to different dosages of AgNPs (7.5, 30 or 120 mg kg(-1) ). Toxic effects were assessed via general behavior, serum biochemical parameters and histopathological observation of the mice. Biokinetics and tissue(More)
Exposure to titanium dioxide nanoparticles (TiO(2) NPs) has been demonstrated to result in pulmonary inflammation in animals; however, very little is known about the molecular mechanisms of pulmonary injury due to TiO(2) NPs exposure. The aim of this study was to evaluate the oxidative stress and molecular mechanism associated with pulmonary inflammation in(More)
Correction After publication of this article [1], the authors became aware of the fact that the original version of this article missed equal contributor and corresponding author information. Intragastric exposure to titanium dioxide nanoparticles induced nephrotoxicity in mice, assessed by physiological and gene expression modifications. which permits(More)