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Sustained response to deep brain stimulation in LRRK2 parkinsonism with the Y1699C mutation.
- L. Perju-Dumbrava, M. McDonald, A. Kneebone, R. Long, D. Thyagarajan
- Journal of Parkinson's disease
Although effective deep brain stimulation of the subthalamic nucleus (STN-DBS) is reported in G2019S leucine-rich repeat kinase 2 (LRRK2) parkinsonism, response to surgery in other LRRK2 mutations… Expand
Pilot study of SGN-15 immunoconjugate with docetaxel as first line therapy for NSCLC with PET assessment of response
7299 Background: NSCLC cells express tumor antigens, including Lewis Υ (Ley). SGN-15 is a novel antibody-drug conjugate that delivers doxorubicin to cells expressing Ley and has synergistic activity… Expand
PO019 Contractures and glycine receptor antibody encephalitis
- Omar Salim, M. McDonald, Niall MacDougll, A. Davidson
- Journal of Neurology, Neurosurgery, and…
- 20 November 2017
68 year lady with 3 weeks of dysphagia, intermittent diplopia and bilateral ptosis. MRI brain and AChR antibody were normal. This progressed into multiple cranial nerve and cerebellar signs with… Expand