This paper presents my personal account of research on CO 2 fixation from when I began these studies as a postdoctoral student in the early 1970s. It traces interests in microbial ribulose bisphosphate carboxylase/oxygenase (Rubisco) and considers early breakthroughs on the isolation, characterization, and significance of this enzyme from nonsulfur purple… (More)
Introduction: Over the last two Earth years the Mars Exploration Rover Opportunity has investigated, via remote sensing and in situ observations, an extensive occurrence of hematite and sulfate-salt rich sedimentary bedrock exposures in crater walls and plains surfaces . Farrand et al.  have described the major spectral properties of bedrock in the… (More)
Syn-and anti-benzo[a]pyrene diol epoxides elicit a concentration-dependent nicking of superhelical Col E1 DNA in an in vitro reaction monitored by agarose gel electrophoresis and electron microscopy. This strand scission represents less than 1 percent of the DNA modification by diol epoxide. Kinetic analysis implicates the formation of unstable… (More)
Chemical analyses have been made of a number of plant species in order to assess their suitability as renewable sources of hydrocarbon-like photosynthetic products. Yields of rubber and wax, glycerides, isoprenoids, and other terpenoids were estimated. Individual sterols were identified in latex from some species.
A selection of new plant sources with high potential for production of chemicals and liquid fuels is reviewed. Some productivity data are given, and suggestions are made for modification of both the product character and the productivity of the plants.
A simple method is described for the freeze-fracture in situ of monolayer cultures grown on gold carriers coated with a thin layer of silicon monoxide. Preliminary observations on 3T3 mouse embryo fibroblasts indicate that this technique exposes large areas of cell membrane, making it possible to determine how areas of membrane specialization are related to… (More)
Any opinions expressed in this memoir are those of the author(s) and do not necessarily reflect the views of the National Academy of Sciences.