Melody A. Verges

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A technique and loading apparatus have been developed which allow ball grid array (BGA) packages to be visually inspected during high cycle vibration testing. This system provides controls for varying the cycling frequency and magnitude of the applied load. The failures of solder interconnects in BGA specimens were recorded by a direct visual monitoring(More)
The expression and intracellular localization of cyclin A and cdk2 have been analyzed in rat liver cells proliferatively activated in vivo by a partial hepatectomy. Western blot analysis revealed that cyclin A started to increase during G1 (at 6 h after hepatectomy) reaching maximal levels during S phase (at 18 h). Cdk2 began to increase during late G1 (at(More)
Recent studies have implicated the cell cycle kinase cdc2 and cyclin A in the inhibition of the fusion of endocytic vesicles in vitro during mitosis. However, the presence of cyclins or their associated cyclin dependent kinases (cdks) in the endocytic fractions have not been reported. Using Western-blotting and immunocytochemistry approaches with different(More)
Asialoglycoprotein receptors, responsible for the removal of circulating asialoglycoproteins by the liver, are located in at least two different membrane locations in hepatocytes. Receptors on the cell surface account only for a minor proportion (20-36%), for the majority of receptors in the liver are located intracellularly, mainly in the endocytic(More)
Liver plasma membranes originating from the sinusoidal, lateral and canalicular domains and 'early' and 'late' endosomes were prepared from rats injected with [32P]orthophosphate. The phosphorylated polypeptides in these subcellular fractions, resolved by gel electrophoresis, were analysed and compared with those obtained by in vitro phosphorylation of the(More)
Antibodies raised to two membrane proteins present in rat liver endosomal fractions were used to study changes occurring in the endocytic compartment of hepatocytes during liver regeneration. Antibodies to the 42-kDa subunit (RHL-1) of the asialoglycoprotein receptor showed, by Western blotting of liver microsomes and endosomes, that there was a reduced(More)
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