Melle Sieswerda

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Genes that play an important role in tumorigenesis are expected to show association between DNA copy number and RNA expression. Optimal power to find such associations can only be achieved if analysing copy number and gene expression jointly. Furthermore, some copy number changes extend over larger chromosomal regions affecting the expression levels of(More)
4 Example: Breast cancer 3 4.1 Data sets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 4.2 Assembling the data . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 4.3 Applying the model . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 4.4 Plotting and tabulating the P-values .(More)
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