Melissa Sims

Learn More
Apical root surfaces covered by cellular cementum are rapidly subjected to resorption under orthodontic loads of varying magnitude and duration. Within the experimental parameters employed, the intrusive forces applied to the teeth produced a striking increase in root resorption compared with the control teeth. The amount of resorption increased markedly(More)
The effects of rapid maxillary expansion on the external root structure of thirteen appliance-attached and five unattached maxillary first premolars from nine patients have been investigated with the scanning electron microscope (SEM). Topographic features of cementum and dentine resorption, as well as initial and subsequent remineralization changes, are(More)
BACKGROUND A current theory holds that oxidative stress, ie, an imbalance between maternal prooxidants and antioxidants, is a component of preeclampsia. It is uncertain whether such an imbalance occurs before clinical recognition of the syndrome or whether it is related to diet. OBJECTIVE We measured urinary excretion of the isoprostane(More)
This study was designed to investigate human repair and reattachment of principal periodontal fibers in areas of resorption on anchor premolar root surfaces following rapid maxillary expansion. Maxillary first premolar teeth were obtained from patients requiring rapid maxillary expansion. Extraction of the teeth was scheduled after periods of retention(More)
BACKGROUND Few data exist on the effects of the 2 most abundant isomers of vitamin E (alpha- and gamma-tocopherols) on fetal growth. OBJECTIVE We measured maternal plasma concentrations of alpha- and gamma-tocopherols and examined their relation with measures of fetal growth. We also examined the relation, controlled for associated maternal factors, of(More)
The aim of this case-control study was to test the hypothesis that maxillary morphology differs between obstructive sleep apnoea (OSA) patients and non-snoring, non-apnoeic subjects. Forty randomly selected patients [36 M, 4 F; mean age 49 +/- 2 (SEM) years] with varying degrees of OSA (mean Apnoea/Hypopnoea Index 32 +/- 4/hour) were compared with 21(More)
Immunolabelling of the normal rat molar periodontal ligament (PDL) with RECA-1 antibody, an endothelial cell surface marker, demonstrated the endothelium in the different categories of blood vessels. The intensity of immunolabelling was similar for venous capillaries (VC), post-capillary-sized venules (PCV), and collecting venules (CV). Arterial capillaries(More)
Extrusive tooth loads, simulating short-term orthodontic movements, have not previously been used for transmission electron microscopic quantification of their effects on the periodontal ligament vessels. In this study, a continuous extrusive load of 1.0 N, applied to the rat maxillary first molar for 30 minutes, produced statistically significant changes(More)