• Publications
  • Influence
Suppression of non-specific adsorption using sheath flow.
The use of a confining sheath fluid within a microfluidic channel in order prevent non-specific adsorption of analytes to the walls of microchannels is demonstrated. A sheath-flow channel fabricatedExpand
  • 31
  • 1
Demonstration of multi-analyte patterning using piezoelectric inkjet printing of multiple layers.
Patterning substrates with biological reagents is a critical component of biosensor development. Many applications require multi-analyte patterning capabilities, with a need to deposit severalExpand
  • 45
  • PDF
High-throughput screening of enzyme inhibition using an inhibitor gradient generated in a microchannel.
A new rapid microfluidic method for measuring enzyme inhibition is presented. The assay relies upon the creation of a uniform concentration of substrate and a microfluidically generated concentrationExpand
  • 26
  • PDF
Diffusion based analysis in a sheath flow microchannel: the sheath flow T-sensor.
This paper describes a microfluidic channel that allows for diffusion-based analysis of adsorbing species without passivation of the channel surfaces. The sheath flow configuration was used toExpand
  • 23
Lateral spread of an amplification signal using an enzymatic system on a conductive surface.
In this letter, we report a novel signal amplification phenomenon that rapidly and dramatically increases both the magnitude and the lateral extent of the original signal. This phenomenon utilizes anExpand
  • 6
Investigation of heterogeneous electrochemical processes using multi-stream laminar flow in a microchannel.
A multi-component microfluidic electrochemical cell is shown to be a useful analytical tool for probing complex coupled processes in electrolytic systems. We recently reported an enzymatic signalExpand
  • 4
Spreading small signals over large areas