• Publications
  • Influence
Roles of Macrophages in Flow-Induced Outward Vascular Remodeling
Sustained hemodynamic stresses, especially sustained high blood flow, result in flow-induced outward vascular remodeling. Mechanisms that link hemodynamic stresses to vascular remodeling are not wellExpand
  • 46
  • 3
Label-free isolation of prostate circulating tumor cells using Vortex microfluidic technology
There has been increased interest in utilizing non-invasive “liquid biopsies” to identify biomarkers for cancer prognosis and monitoring, and to isolate genetic material that can predict response toExpand
  • 34
  • 2
Evaluation of PD-L1 expression on vortex-isolated circulating tumor cells in metastatic lung cancer
Metastatic non-small cell lung cancer (NSCLC) is a highly fatal and immunogenic malignancy. Although the immune system is known to recognize these tumor cells, one mechanism by which NSCLC can evadeExpand
  • 33
  • 2
Classification of large circulating tumor cells isolated with ultra-high throughput microfluidic Vortex technology
Circulating tumor cells (CTCs) are emerging as rare but clinically significant non-invasive cellular biomarkers for cancer patient prognosis, treatment selection, and treatment monitoring. CurrentExpand
  • 91
  • 1
  • PDF
Suppression of MMP-9 by doxycycline in brain arteriovenous malformations.
BACKGROUND The primary aim of this study is to demonstrate the feasibility of utilizing doxycycline to suppress matrix metalloproteinase-9 (MMP-9) in brain arteriovenous malformations (AVMs). Expand
  • 24
  • 1
Suppression of MMP-9 by doxycycline in brain arteriovenous malformations
BackgroundThe primary aim of this study is to demonstrate the feasibility of utilizing doxycycline to suppress matrix metalloproteinase-9 (MMP-9) in brain arteriovenous malformationsExpand
  • 38
Label-free enumeration, collection and downstream cytological and cytogenetic analysis of circulating tumor cells
Circulating tumor cells (CTCs) have a great potential as indicators of metastatic disease that may help physicians improve cancer prognostication, treatment and patient outcomes. Heterogeneous markerExpand
  • 30
Regulation of tie2 expression by angiopoietin--potential feedback system.
To study a potential feedback system in the angiopoietin (Ang)-Tie2 system, the authors examined effects of Ang1 and Ang2 on Tie2 expression on human umbilical vein endothelial cells (HUVECs) with orExpand
  • 15
Abrupt increase in rat carotid blood flow induces rapid alteration of artery mechanical properties.
Vascular remodeling is essential to proper vessel function. Dramatic changes in mechanical environment, however, may initiate pathophysiological vascular remodeling processes that lead to vascularExpand
  • 10
  • PDF
Regulation of tie2 expression by angiopoietin--potential feedback system.
To study a potential feedback system in the angiopoietin (Ang)-Tie2 system, the authors examined effects of Ang1 and Ang2 on Tie2 expression on human umbilical vein endothelial cells (HUVECs) with orExpand
  • 18