Melissa Cheung

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OBJECTIVE To characterize consumers' attitudes about personal health records (PHRs), electronic tools that enable consumers to securely access, manage, and share their health information, in a community participating in health information technology initiatives. STUDY DESIGN Cross-sectional study. METHODS A random-digit-dial telephone survey about PHRs(More)
Small guanosine triphosphatases (GTPases) become activated when GDP is replaced by GTP at the highly conserved nucleotide binding site. This process is intrinsically very slow in most GTPases but is significantly accelerated by guanine nucleotide exchange factors (GEFs). Nucleotide exchange in small GTPases has been widely studied using spectroscopy with(More)
Poly(ADP-ribosyl)ation by poly(ADP-ribose) polymerases regulates the interaction of many DNA damage and repair factors with sites of DNA strand lesions. The interaction of these factors with poly(ADP-ribose) (PAR) is mediated by specific domains, including the recently identified PAR-binding zinc finger (PBZ) domain. However, the mechanism governing these(More)
The mitochondrial electron transport chain (ETC) includes an alternative oxidase (AOX) that may control the generation of reactive oxygen species (ROS) and reactive nitrogen species (RNS). ROS and RNS act as signaling intermediates in numerous plant processes, including stomatal movement. The role of AOX in controlling ROS and RNS concentrations under both(More)
Business process modelling is the core activity in Business Process Driven SOA. ARIS is a Business Process Analysis (BPA) tool adequate for analyzing and designing business processes, while the execution and monitoring of these processes is empowered by Cordys as Business Process Management Suite (BPMS). The challenge is to enable iterative round-trip(More)
BACKGROUND Thymus transplantation is a promising strategy for the treatment of athymic complete DiGeorge syndrome (cDGS). METHODS Twelve patients with cDGS underwent transplantation with allogeneic cultured thymus. OBJECTIVE We sought to confirm and extend the results previously obtained in a single center. RESULTS Two patients died of pre-existing(More)
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