Melissa Burgess

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A polymerase chain reaction (PCR) assay that identifies and differentiates wild-type (wt) and vaccine strains of varicella-zoster virus (VZV) was used to determine if VZV strains with restriction fragment length polymorphisms resembling those of the Japanese Oka vaccine strain were present in the wt pool outside of Japan. Virus samples (n = 114) from(More)
No longer is histology solely predictive of cancer treatment and outcome. There is an increasing influence of tumor genomic characteristics on therapeutic options. Both breast and ovarian cancers are at higher risk of development in patients with BRCA 1/2-germline mutations. Recent data from The Cancer Genome Atlas and others have shown a number of genomic(More)
Immunologic approaches to cancer are over a century old. Over the years, the strategy has been fine-tuned from inciting infections in subjects to inhibiting negative regulatory signals from the innate immune system. Sarcomas are among the first tumors to be considered for immune interventions. From Coley's toxin to cytokine-based therapies to adoptive cell(More)
OPINION STATEMENT Current therapies in advanced sarcomas are primarily based on cytotoxic chemotherapy and have modest efficacy coupled with significant toxicity. Little progress has been made in the field since imatinib was approved for the treatment of gastrointestinal stromal tumor (GIST) in 2002 despite the recent FDA approval of the multi-tyrosine(More)
Behavioral studies indicate that adult mountain gorillas (Gorilla beringei) are the most terrestrial of all nonhuman hominoids, but that infant mountain gorillas are much more arboreal. Here we examine ontogenetic changes in diaphyseal strength and length of the femur, tibia, humerus, radius, and ulna in 30 Virunga mountain gorillas, including 18 immature(More)
One hundred and three women who were habitual distance runners and 74 age-matched physically inactive women provided three-day diet records. Intergroup differences in intakes of energy nutrients, micronutrients, cholesterol and fiber were evaluated via analysis of variance and, to assess qualitative differences, via analysis of covariance with total caloric(More)
Because of its completeness, the juvenile Homo ergaster/erectus KNM-WT 15000 has played an important role in studies of the evolution of body form in Homo. Early attempts to estimate his adult body size used modern human growth models. However, more recent evidence, particularly from the dentition, suggests that he may have had a more chimpanzee-like growth(More)
The purpose of this study was to determine the validity of five field tests (FTs) of upper body muscular strength and endurance (UBMSE) in 9-10-year-old children. Ninety-four children (38 boys, 56 girls) performed five FTs of UBMSE: pull-ups, flexed arm hang, push-ups, Vermont modified pull-ups (VMPU), and New York modified pull-ups. They also performed(More)
O1 IL-15 primes an mTOR-regulated gene-expression program to prolong anti-tumor capacity of human natural killer cells Andreas Lundqvist, Vincent van Hoef, Xiaonan Zhang, Erik Wennerberg, Julie Lorent, Kristina Witt, Laia Masvidal Sanz, Shuo Liang, Shannon Murray, Ola Larsson, Rolf Kiessling, Yumeng Mao Karolinska Institutet, Stockholm, Stockholms Lan,(More)
Little is known about reading ability among doctoral students. Thus, we used a multi-stage mixed analysis to examine 205 doctoral students’ levels of reading ability, their perceptions of barriers that prevented them from reading empirical articles, and the relationship between these two sets of constructs. Approximately 10% of doctoral students attained(More)