Melina Gattellari

Learn More
BACKGROUND AND PURPOSE Existing epidemiological studies of Myasthenia Gravis have generally examined small populations. Few national studies have been conducted, and published incidence and prevalence rates vary widely. We report one of the largest national studies of Myasthenia Gravis, and the first incidence and prevalence rates for Australia. METHODS(More)
BACKGROUND AND PURPOSE Anticoagulation reduces the risk of stroke in nonvalvular atrial fibrillation yet remains underused. We explored barriers to the use of anticoagulants among Australian family physicians. METHODS The authors conducted a representative, national survey. RESULTS Of the 596 (64.4%) eligible family physicians who participated, 15.8%(More)
BACKGROUND AND PURPOSE In randomized trials, acute stroke units are associated with improved patient outcomes. However, it is unclear whether this evidence can be successfully translated into routine clinical practice. We aimed to determine the effect of a coordinated rollout of funding for 22 stroke units on patient outcomes in Australia. METHODS A(More)
BACKGROUND AND PURPOSE There is a lack of modern-day data quantifying the effect of transient ischemic attack (TIA) on survival, and recent data do not take into account expected survival. METHODS Data for 22 157 adults hospitalized with a TIA from July 1, 2000, to June 30, 2007, in New South Wales, Australia, were linked with registered deaths to June(More)
BACKGROUND Compelling evidence shows that appropriate use of anticoagulation in patients with nonvalvular atrial fibrillation reduces the risk of ischaemic stroke by 67% and all-cause mortality by 26%. Despite this evidence, anticoagulation is substantially underused, resulting in avoidable fatal and disabling strokes. METHODS DESPATCH is a cluster(More)
HYPOTHESIS Not all Australian surgeons are aware of the status of the current evidence for the management of colorectal cancer. DESIGN Postal survey of Fellows of the Royal Australasian College of Surgeons. PARTICIPANTS One hundred ninety-five surgeons (127 general surgeons and 68 subspecialist colorectal surgeons) from a response fraction of 89%. (More)
BACKGROUND A recent systematic review of epidemiological studies reported intracerebral hemorrhage (ICH) incidence and mortality as unchanged over time; however, comparisons between studies conducted in different health services obscure assessment of trends. We explored trends in ICH rates in a large, representative population in New South Wales,(More)
BACKGROUND General practitioners (GPs) are ideally placed to bridge the widely noted evidence-practice gap between current management of NVAF and the need to increase anticoagulant use to reduce the risk of fatal and disabling stroke in NVAF. We aimed to identify gaps in current care, and asked GPs to identify potentially useful strategies to overcome(More)
BACKGROUND Suboptimal uptake of anticoagulation for stroke prevention in atrial fibrillation has persisted for over 20 years, despite high-level evidence demonstrating its effectiveness in reducing the risk of fatal and disabling stroke. METHODS The STOP STROKE in AF study is a national, cluster randomised controlled trial designed to improve the uptake(More)