Melchor Bruno Lemp

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PURPOSE To evaluate the 2-year effects of intrastromal corneal ring segments (INTACS) on the corneal endothelium. METHODS Non-contact specular microscopy was performed as a subgroup test in a Phase III clinical trial. Endothelial cell images were collected before surgery and at 6, 12, and 24 months after surgery at the central and peripheral (6 and 10(More)
ACTH secreting macroadenomas and pituitary apoplexy are unusual in Cushing disease. In the few cases reported in the literature, they have been found in long term hypercortisolism. We communicate a 43 yr old woman with a 4 year evolution Cushing syndrome, who developed sudden cephalea and oftalmoplejia. A Computed Tomography of the pituitary fossa disclosed(More)
We performed a retrospective analysis of forty-four patients, collected between 1996 and May of 2017. Thirtysix CD (29 females/7 males; mean age: 36.7 ± 14.6 years), confirmed by increased ACTH (70.5 ± 47 pg/ml), cortisol suppression (more than 50%) in the Tyrrel test, pituitary adenoma in radiological examinations and at the surgical specimen, an adenoma(More)
Background Nummular headache is a rare, recently described topographic headache defined by the circumscribed coin-shaped area of pain. It is classified as a primary headache. There is debate about whether it is due to a peripheral or central disturbance, and its relationship to migraine. Case reports We report two patients with presumed nummular headache(More)
BACKGROUND Growth hormone (GH) producing adenomas, frequently express several hormones. This condition could confer them a higher proliferative capacity. Ki-67 is a nuclear protein antigen that is a marker for proliferative activity. AIM To measure the immunohistochemical hormone expression in pituitary adenomas, excised from patients with acromegaly. To(More)
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