Melantha E. Jackson

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Since RNAs lie at the center of most cellular processes, there is a need for synthesizing large amounts of RNAs made from stable isotope-labeled nucleotides to advance the study of their structure and dynamics by nuclear magnetic resonance (NMR) spectroscopy. A particularly effective means of obtaining labeled nucleotides is to harvest these nucleotides(More)
Escherichia coli (E. coli) is an ideal organism to tailor-make labeled nucleotides for biophysical studies of RNA. Recently, we showed that adding labeled formate enhanced the isotopic enrichment at protonated carbon sites in nucleotides. In this paper, we show that growth of a mutant E. coli strain DL323 (lacking succinate and malate dehydrogenases) on(More)
Title of Document: ELEVATED TEMPERATURE EFFECTS ON CAROTENOID BIOSYNTHESIS IN THE DIPLOID STRAWBERRY, FRAGARIA VESCA Melantha E. Jackson, Doctor of Philosophy, 2015 Directed By: Professor Herman Sintim Department of Chemistry and Biochemistry Carotenoids, a subfamily of the isoprenoids, are one of the most diverse classes of secondary metabolites(More)
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