Melanie M. Wall

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The human X chromosome has a unique biology that was shaped by its evolution as the sex chromosome shared by males and females. We have determined 99.3% of the euchromatic sequence of the X chromosome. Our analysis illustrates the autosomal origin of the mammalian sex chromosomes, the stepwise process that led to the progressive loss of recombination(More)
BACKGROUND This study aims to identify correlates of fruits and vegetables from within the domains of personal factors (taste preferences, health/nutrition attitudes, weight/body concerns, and self-efficacy), behavioral factors (meal frequency, fast food intake, and weight control behaviors), and socio-environmental factors (social support for healthy(More)
OBJECTIVE The aim of this study was to investigate the potential of mindfulness-based stress reduction (MBSR) as a treatment for chronic primary insomnia. DESIGN A randomized controlled trial was conducted. SETTING The study was conducted at a university health center. PATIENTS Thirty adults with primary chronic insomnia based on criteria of the(More)
BACKGROUND Weight-related problems, including obesity, eating disorders, and disordered eating, are major public health problems in adolescents. The identification of shared risk and protective factors for these problems can guide the development of relevant interventions to a broad spectrum of weight-related problems. This paper examines the prevalence and(More)
BACKGROUND Previous research suggests that various types of childhood maltreatment frequently co-occur and confer risk for multiple psychiatric diagnoses. This non-specific pattern of risk may mean that childhood maltreatment increases vulnerability to numerous specific psychiatric disorders through diverse, specific mechanisms or that childhood(More)
PURPOSE Obtaining stature, weight, and body mass index (BMI) from self-reports rather than by direct measurements is highly attractive economically and logistically, but there are few data available for adolescents that allow evaluation of potential sources of reporting bias. Because self-reports are based on self perceptions, personal characteristics of(More)
OBJECTIVE To determine if adolescents who report dieting and different weight-control behaviors are at increased or decreased risk for gains in body mass index, overweight status, binge eating, extreme weight-control behaviors, and eating disorders 5 years later. DESIGN Population-based 5-year longitudinal study. PARTICIPANTS Adolescents (N=2,516) from(More)
OBJECTIVE To identify correlates of calcium, dairy, and milk intakes among male and female adolescents. DESIGN Cross-sectional study design. Adolescents self-reported measures pertaining to correlates on the Project EAT (Eating Among Teens) survey and completed a food frequency questionnaire at school. SUBJECTS/SETTING Subjects were a total of 4,079(More)
Multivariate comorbidity research indicates mood and anxiety (internalizing) disorders share one or more common liabilities, but categorical, dimensional, and hybrid accounts of these liabilities have not been directly compared. We modeled seven internalizing disorders in a nationally representative sample of 43,093 individuals via confirmatory factor,(More)
BACKGROUND Disordered eating behaviors are prevalent in adolescence and can have harmful consequences. An important question is whether use of these behaviors in adolescence sets the pattern for continued use into young adulthood. OBJECTIVE To examine the prevalence and tracking of dieting, unhealthy and extreme weight control behaviors, and binge eating(More)