Melanie Kleiner

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Functional interactions between different brain regions require connecting fiber tracts, the structural basis of the human connectome. To assemble a comprehensive structural understanding of neural network elements from the microscopic to the macroscopic dimensions, a multimodal and multiscale approach has to be envisaged. However, the integration of(More)
OBJECTIVES Standard methods to examine nasal flow are experimental and do not yield locally detailed results. Using the Lattice-Boltzmann method (LBM), we computed nasal air flow and investigated the relationship between nasal obstruction and anatomical conditions. Because of its mathematical structure, the LBM can be immediately applied to various nasal(More)
Polarized light imaging (PLI) enables the visualization of fiber tracts with high spatial resolution in microtome sections of postmortem brains. Vectors of the fiber orientation defined by inclination and direction angles can directly be derived from the optical signals employed by PLI analysis. The polarization state of light propagating through a rotating(More)
Kurzfassung. Bei Frakturen des Orbitabodens kann ein Titangitter zur Rekonstruktion operativ eingesetzt werden. In dieser Arbeit wird ein Planungswerkzeug entwickelt, welches mit Hilfe eines aktiven Konturmodells die Orbita in CT Daten segmentiert, ihr Volumen berechnet und visualisiert. Neben den technischen Integrationsstufen der Funktionsund(More)
3D polarized light imaging (3D-PLI) has been shown to measure the orientation of nerve fibers in post mortem human brains at ultra high resolution. The 3D orientation in each voxel is obtained as a pair of angles, the direction angle and the inclination angle with unknown sign. The sign ambiguity is a major problem for the correct interpretation of fiber(More)
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