Melanie Kercher

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Investigators tested the hypothesis that administration of the NMDA antagonist ketamine would result in differential effects on activity levels in rats depending upon the age and the sex of the animal. Twenty-two-, 35-, and 50-day-old rats were given doses of ketamine (0.0 or 10.0 mg/kg) and tested for open-field activity and frequencies of reverse(More)
ROCEDURES FOR THE DETECTION OF SUGAR IN URINE are among the oldest tests known in clinical chemistry. Legends going back to earliest times describe the attraction of insects to urine containing sugar. In many instances it is difficult to separate legend from reality in tracing the history of tests for glycosuria. Among such pioneer American clinical(More)
Investigators tested the notion that simulating a mother rat's transporting of her pup to a novel environment would result in a reduction in subsequent activity in that infant. Fourteen-day-old rats were tested for activity levels, rearing and turning in an open-field after having undergone one of the three conditions: transport response elicitation;(More)
OBJECTIVE To determine whether the amount of intrauterine tissue was prognostic of the risk of complications associated with the management of nonviable pregnancies diagnosed in the first trimester before cervical dilatation (termed here impending abortion) with either expectant observation or elective curettage. DESIGN Historic cohort study. SETTING(More)
In considering possible effects of ketamine, and its interactions with drugs that might be administered following ketamine abuse, researchers investigated the effects of administering combinations of saline, naloxone, and/or ketamine on open-field activity levels and frequencies of turning, reverse locomotion, head weaving, and rearing in 50-day-old rats.(More)
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