Melanie Jensen

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The aim of this study was to identify novel antibodies directed against cytosolic keratinocyte-specific antigens from a phage display antibody repertoire by using phage display subtraction. Phage display is a method of displaying foreign molecules on the surface of filamentous bacteriophage particles. It allows the interaction between two cognate molecules(More)
The G domain of elongation factor Tu (EF-Tu), representing the N-terminal half of the factor according to its three-dimensional model traced at high resolution, has been isolated by genetic manipulation of tufA and purified to homogeneity. The G domain, whose primary structure shares homology with the eukaryotic protein p21, is capable of supporting the(More)
The guanine-nucleotide-binding domain (G domain) of elongation factor Tu(EF-Tu) consisting of 203 amino acid residues, corresponding to the N-terminal half of the molecule, has been recently engineered by deleting part of the tufA gene and partially characterized [Parmeggiani, A., Swart, G. W. M., Mortensen, K. K., Jensen, M., Clark, B. F. C., Dente, L. and(More)
In the book Tilings and Patterns by B. Grunbaum and G. S. Shep-hard, the problem of classifying the uniform edge-c-colorings of Archimedean tilings of the Euclidean plane is posed. This article provides such a classification. A plane tiling T is a countable family of closed topological disks T = {T 1 , T 2 , ...} that cover the Euclidean plane E 2 without(More)
We study the advection-diffusion equation −ε∆u + b · ∇u = f in Ω ⊂ R d (1a) u = 0 on ∂Ω (1b) in a polygonal domain Ω with ε ∈ R + , b ∈ W ∞ (div, Ω) and f ∈ L 2 (Ω) where we define W ∞ (div, Ω) := {v ∈ [L ∞ (Ω)] d ; (∇ · v) ∈ L ∞ (Ω)}. It is a standard result that (1) has a unique solution in H 1 0 (Ω) provided that − 1 2 ∇ · b ≥ 0. The first term in (1a)(More)
Mutation of Pro82 into Thr, a residue situated in the second element (D80CPG83) of the consensus sequence proposed to interact with GTP/GDP in GTP-binding proteins was introduced via site-directed mutagenesis in the isolated guanine nucleotide-binding domain (G domain) of elongation factor Tu. G domainPT82 displays virtually no GTPase activity. As a major(More)
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