Melanie Goodman Keiser

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INTRODUCTION Although burst spinal cord stimulation (SCS) has been reported to reduce neuropathic pain, no study has explicitly investigated how the different parameters that define burst SCS may modulate its efficacy. The effectiveness of burst SCS to reduce neuronal responses to noxious stimuli by altering stimulation parameters was evaluated in a rat(More)
To the Editor: INTRODUCTION Melorheostosis (also known as Leri’s disease) is a rare, nonhereditary, sclerotic bone dysplasia that is characterized by a thickening of the bone (1,2). On X-ray, the appearance of melorheostosis can be likened to the flowing wax of a melting candle. Although the disease can present at any age, the peak age range is from 5 to 20(More)
Since the 1900s, the number of deaths attributable to cardiovascular disease has steadily risen. With the advent of antihypertensive drugs and non-invasive surgical procedures, such as intravascular stenting, these numbers have begun to level off. Despite this trend, the number of patients diagnosed with some form of cardiovascular disease has only(More)
OBJECTIVES This study compares the effects of constant current (CC) and constant voltage (CV) spinal cord stimulation (SCS) at various frequencies and intensities on standard nociceptive measurements in rats, the visceromotor reflex (VMR) and neuronal activity, during noxious visceral and somatic stimuli. MATERIALS AND METHODS Abdominal muscle(More)
Chronic pain caused by lack of blood flow is known as ischemic pain. Neurostimulation, the application of electrical currents through a region of the body, is effective for pain modulation, and it is hypothesized that this can be explained by the gate control theory and alterations of the sympathetic output initiated by the metaboreflex. The decrease of(More)
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