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BACKGROUND Zika virus (ZIKV) is a little known flavivirus that caused a major outbreak in 2007, in the South-western Pacific Island of Yap. It causes dengue-like syndromes but with milder symptoms. In Africa, where it was first isolated, ZIKV is mainly transmitted by sylvatic Aedes mosquitoes. The virus has also been isolated from Ae. aegypti and it is(More)
CONTEXT Ages at menarche and menopause are associated with cardiovascular disease (CVD), diabetes, and osteoporosis in Caucasian women, but associations remain unexplored in Chinese women. OBJECTIVE The purpose of this study was to assess associations between age at menarche and menopause with CVD, diabetes, and osteoporosis in Chinese women. DESIGN AND(More)
OBJECTIVE This study investigated the impact of family history of diabetes (FHD) on β-cell function among Chinese with normal glucose tolerance. RESEARCH DESIGN AND METHODS A multistage, stratified, cluster random sampling method was used to select a provincially representative sample from Fujian Province. Eventually, a total of 1,183 subjects were(More)
OBJECTIVE To investigate the association between family history and clinical symptoms of polycystic ovary syndrome (PCOS) that were thought to be inherited, by treating women with PCOS with contraceptive pills and metformin, and assessing outcomes. METHODS Of 164 women with PCOS, 49 with menstrual abnormalities, hyperandrogenism, and abnormal glucose(More)
CONTEXT Associations between sleep, daytime nap duration, and osteoporosis remain uncertain, and far less is even known about the influence of sex, menopause, and sleep quality on them. OBJECTIVE The objective of the study was to test the associations between sleep, daytime nap duration, and osteoporosis and whether they vary by sex, menopause, and sleep(More)
BACKGROUND Zika (ZIKV) and Chikungunya (CHIKV) viruses are emerging Aedes-borne viruses that are spreading outside their known geographic range and causing wide-scale epidemics. It has been reported that these viruses can be transmitted efficiently by Ae. aegypti. Recent studies have shown that Ae. aegypti when transinfected with certain Wolbachia strains(More)
The causes of disorders of the venous return of blood to the heart in development of acute experimental cardiovascular insufficiency were studied. It was established that grave hemodynamic disturbances in pulmonary circulation are the consequence but not the cause of the sharp decrease of venous blood return to the heart with the development of acute(More)
OBJECTIVE To evaluate the role of apolipoprotein C-I (apoC-I) levels and assess relationships between apoC-I and clinical features in women with polycystic ovary syndrome (PCOS). DESIGN Prospective study. SETTING Reproductive Center of Peking University Third Hospital. PATIENT(S) Thirty patients with PCOS with insulin resistance, 30 patients with PCOS(More)
OBJECTIVE To screen the serum protein expression profiles in patients having polycystic ovary syndrome (PCOS) with or without insulin resistance (IR) and search for discriminatory proteins. DESIGN Cross-sectional study. SETTING Reproductive Center of Peking University Third Hospital. PATIENT(S) Thirty patients with PCOS with IR, 30 patients with PCOS(More)