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Circulating microRNA expressions in colorectal cancer as predictors of response to chemotherapy
TLDR
A group of miRNA predictors in response to chemosensitivity for CRC patients are identified, which could lead to a significant improvement in chemotherapy regimen selection strategy and personalized CRC management. Expand
Transforming Growth Factor (TGF)-β-Induced MicroRNA-216a Promotes Acute Pancreatitis Via Akt and TGF-β Pathway in Mice
TLDR
TGF- β promotes AP by inducing miR-216a targeting PTEN and Smad7, thus through PI3K/Akt and TGF-β feedback pathway, and can be regulated by SB431542 both in mouse model and AR42J cells. Expand
Role of CIP4 in high glucose induced epithelial--mesenchymal transition of rat peritoneal mesothelial cells
TLDR
CIP4 promotes high glucose-induced EMT through PI3K-Akt signaling pathway in RPMCs through which CIP4-siRNA transfection can reverse EMT of RPMCs. Expand