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Glutathione peroxidase 3 (GPX3) suppresses the growth of melanoma cells through reactive oxygen species (ROS)‐dependent stabilization of hypoxia‐inducible factor 1‐α and 2‐α
- Zihan Yi, L. Jiang, +9 authors Y. Zhu
- Chemistry, Medicine
- Journal of cellular biochemistry
- 1 November 2019
In this study, we aimed to explore the mechanism of glutathione peroxidase 3 (GPX3) in the growth of malignant melanoma (MM) cells by hypoxia‐inducible factor‐1α (HIF1‐α) and HIF2‐α regulating the… Expand
Garlic-derived bioactive compound S-allylcysteine inhibits cancer progression through diverse molecular mechanisms.
- Yannick Luther Agbana, Yueli Ni, +5 authors Yuechun Zhu
- Biology, Medicine
- Nutrition research
- 18 November 2019
The purpose of this review is to discuss the molecular mechanisms underlying the anticancer properties of S-allylcysteine (SAC). Over the decades, evidence derived from in vitro and in vivo studies… Expand
[Unsaturated fatty acid of Actinidia chinesis planch seed oil (kiwi fruit essence) inhibits growth and metastasis of transplanted tumor in lung adenocarcinoma mice by up-regulating EHD2 expression].
- Lijing Liu, Meiling Zhou, Z. Chen, Jianbin He
- Biology, Medicine
- Xi bao yu fen zi mian yi xue za zhi = Chinese…
- 1 July 2020
Objective To observe the role of Eps15 homology domain containing protein 2 (EHD2) in the inhibitive effects of unsaturated fatty acid of Actinidia chinesis planch seed oil (kiwi fruit essence) on… Expand
TAT-modified serum albumin nanoparticles for sustained-release of tetramethylpyrazine and improved targeting to spinal cord injury
Background Spinal Cord injury (SCI) is a kind of severe traumatic disease. The inflammatory response is a significant feature after SCI. Tetramethylpyrazine (TMP), a perennial herb of umbelliferae,… Expand
Modified and simplified clinically important deterioration: multidimensional indices of short-term disease trajectory to predict future exacerbations in patients with chronic obstructive pulmonary…
- Yiyang Zhao, C. Liu, +11 authors P. Chen
- Therapeutic advances in respiratory disease
- 1 December 2020
Background and aims: Various prediction indices based on the single time point observation have been proposed in chronic obstructive pulmonary disease (COPD), but little was known about disease… Expand
Thrombospondin-4 (TSP4) gene-modified bone marrow stromal cells (BMSCs) promote the effect of therapeutic angiogenesis in critical limb ischemia (CLI) of diabetic rats.
Critical limb ischemia (CLI) is the leading cause of lower limb amputation. Traditional treatments for CLI have limitations. Studies have shown that thrombospondin-4 (TSP4) can promote the growth of… Expand