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OBJECTIVE To explore the effectiveness of neurorehabilitative training using an electroencephalogram-based brain- computer interface for hand paralysis following stroke. DESIGN A case series study. SUBJECTS Eight outpatients with chronic stroke demonstrating moderate to severe hemiparesis. METHODS Based on analysis of volitionally decreased amplitudes(More)
BACKGROUND and objective. Unilateral spatial neglect (USN) can interfere with rehabilitation processes and lead to poor functional outcome. The purpose of this study was to determine whether prism adaptation (PA) therapy improves USN and functional outcomes in stroke patients in the subacute stage. METHODS . A multicenter, double-masked, randomized,(More)
OBJECTIVE To identify a most useful and simple clinical screening tool to predict videofluoroscopic aspiration in patients with stroke. DESIGN Factor analysis of multiple dysphagia variables and sensitivity and specificity testing with chi-square test. PATIENTS Sixty-one consecutive stroke patients with symptoms suggestive of dysphagia admitted to a(More)
Pedaling is widely used for rehabilitation of locomotion because it induces similar muscle activity to that observed during locomotion. However, no study has examined the effects of pedaling exercise on intracortical inhibition. The aim of the present study was to investigate the effect of pedaling exercise on short-interval intracortical inhibition (SICI)(More)
It is known that weak transcranial direct current stimulation (tDCS) induces persistent excitability changes in the cerebral cortex. There are, however, few studies that compare the after-effects of anodal versus cathodal tDCS in patients with stroke. This study assessed the after-effects of tDCS over the motor cortex in patients with hemiparetic stroke and(More)
BACKGROUND AND OBJECTIVE We devised a therapeutic approach to facilitate the use of the hemiparetic upper extremity (UE) in daily life by combining integrated volitional control electrical stimulation with a wrist splint, called hybrid assistive neuromuscular dynamic stimulation (HANDS). METHODS Twenty patients with chronic hemiparetic stroke (median 17.5(More)
The mu event-related desynchronization (ERD) is supposed to reflect motor preparation and appear during motor imagery. The aim of this study is to examine the modulation of ERD with transcranial direct current stimulation (tDCS). Six healthy subjects were asked to imagine their right hand grasping something after receiving a visual cue.(More)
To assess the similarity between cortical activities observed during actual and imaginary motor tasks, we evaluated electroencephalography-electromyography (EEG-EMG) coherence during motor task execution (ME) and the same taskrelated EEG power increase (TRPI) during kinesthetic motor imagery (MI). EEGs recorded at the vertex and EMGs recorded at the right(More)
We previously reported the beneficial effect of administering an anti-mouse IL-6 receptor antibody (MR16-1) immediately after spinal cord injury (SCI). The purpose of our present study was to clarify the mechanism underlying how MR16-1 improves motor function after SCI. Quantitative analyses of inflammatory cells using flow cytometry, and(More)
The sensorimotor cortex activity measured by scalp EEG shows coherence with electromyogram (EMG) activity within the 15- to 35-Hz frequency band (β-band) during weak to moderate intensity of isometric voluntary contraction. This coupling is known to change its frequency band to the 35- to 60-Hz band (γ-band) during strong contraction. This study aimed to(More)