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Transforming growth factor-β1 reduces apoptosis via autophagy activation in hepatic stellate cells
The possible functions of TGF-β1-mediated autophagy in the pathological process of liver fibrosis are elucidated and rescued HSC-T6 cells from serum deprivation and reduce apoptosis viaAutophagy induction is elucidated.
β-Nerve growth factor attenuates hepatocyte injury induced by D-galactosamine in vitro via TrkA NGFR.
The results suggested that exogenous β-NGF protects L-02 cells from D-GalN-induced injury through the NGF/TrkA NGFR signaling pathway.
The preliminary clinical observation of Huganjiexian decoction in the treatment of hepatic cirrhosis
Hugenjiexian decoction possessed therapeutic effect on hepatic cirrhosis, it had no obvious toxicity and side effects, and the differences of downward trend of the experimental group were more significant than control group.
Induces Apoptosis in Human Breast Cancer Cells by Stimulating Oxidative Stress and Inhibiting the Notch-Akt Signaling Pathway
ZQL-4c can suppress the growth and invasion of breast cancer by blocking Notch-Akt signaling pathways, which are mainly regulated by ROS-mediated oxidative stress, and might be considered a novel and potential anticancer drug for breast cancer treatment.