Mei-gang Zhu

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OBJECTIVE To study the clinicopathologic features of various types of mature T-cell and natural killer (NK)/T-cell lymphoma in Guangdong, China, with respect to the 2008 WHO classification of lymphoid neoplasms. METHODS Eleven hundred and thirty-seven (1137) cases of mature T-cell or NK/T-cell lymphoma diagnosed during the period from 2002 to 2006 in(More)
OBJECTIVE To investigate the expression of miR-9 in B lymphocytes, B cell lymphoma and classical Hodgkin's lymphoma (cHL) cell lines and its significance. METHODS CD19(+) B lymphocytes were sorted from normal lymph node by magnetic beads. Total cellular micro-RNA was extracted from cHL cell line L428, B cell lymphoma cell lines Ly1 and Ly10 (diffuse large(More)
OBJECTIVE In order to determine the interaction between HBxAg and p53 protein and its role in hepatocarcinogenesis. METHODS Cotransfection was performed using reporter gene, chloramphenical acetyltransferase (CAT), p53 and HBVx gene, and dexamethasone inducible HBx plasmid pMAMHBx was constructed for the experiment. Human hepatoma cell line Hep3B was used(More)
AIM To explore the feasibility of two-dimensional (2D) susceptibility-weighted imaging (SWI) in the visualization of cerebral veins in the foetal brain. MATERIALS AND METHODS Forty-two pregnant healthy women (gestational age: 19-37 weeks, mean: 28.5 ± 7.1 weeks) underwent SWI examination using a 1.5 T MRI system. Two neurologists independently analysed(More)
OBJECTIVE To study the clinicopathologic features of follicular dendritic cell sarcoma (FDCS) and its differential diagnosis. METHODS Ten cases of FDCS were studied by light microscopy, immunohistochemistry and in-situ hybridization. The clinical features and follow-up information were analyzed. RESULTS Amongst the 10 cases of FDCS studied, the(More)
OBJECTIVE To define the clinicopathological features of primary cardiac large B-cell lymphoma. METHOD A case of primary cardiac large B-cell lymphoma was studied with conventional histopathological and immunohistochemical staining in combination with literature review. RESULTS The lesion appeared to originate in the right atrium and involved the venae(More)
OBJECTIVE To study the expressions of latent membrane protein 1 (LMP1), p53 and bcl-2 proteins and investigate their significance in the pathogenesis of Hodgkin's lymphoma. METHODS Immunohistochemical staining was used to examine the expressions of LMP1, bcl-2, and p53 proteins in 31 paraffin-embedded tissue samples from Hodgkin's lymphoma. RESULT The(More)
OBJECTIVE To explore the clinicopathologic features and immunophenotype of hepatosplenic gammadeltaT-cell lymphoma. METHODS A case of hepatosplenic gammadeltaT-cell lymphoma was studied with conventional histopathological and immunohistochemical staining in combination of literature review. RESULTS Diffuse hepatic and splenic enlargement was found in(More)
OBJECTIVE To evaluate significance of immunohistochemistry in Kikuchi's lymphadenitis (KFD). METHODS Biopsy specimens were obtained from 42 KFD cases for microscopic examination after the sections were stained with haematoxylin and eosin, and the immunohistochemical features were analyzed by monoclonal antibodies (CD20, CD8, CD45RO, CD57, CD68) and(More)
BACKGROUND & OBJECTIVE Clonality detection through amplifying immunoglobulin heavy chain (IgH) by polymerase chain reaction (PCR) is a useful tool in diagnosis of lymphoma, but the false negative rate is high, especially in paraffin-embedded tissues. This study was to explore the value of tumor tissue microdissection and combinational detection of IgH and(More)