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Association between Insulin-Like Growth Factor-1 and Uric Acid in Chinese Children and Adolescents with Idiopathic Short Stature: A Cross-Sectional Study
TLDR
A nonlinear relationship between IGF-1 and UA levels in Chinese children and adolescents with ISS suggests that either high or low levels of UA may have an adverse effect on IGF- 1, whereas appropriate UA levels have a beneficial effect. Expand
A heterozygous point mutation of the ANKRD11 (c.2579C>T) in a Chinese patient with idiopathic short stature
Pathogenic variants of ANKRD11 have been reported to cause KBG syndrome characterized by short stature, characteristic facial appearance, intellectual disability, macrodontia, and skeletal anomalies.Expand
Growth hormone peak modifies the effect of BMI on increased systolic blood pressure in children with short stature
TLDR
It was found that SBP was significantly higher in the SGHD group than in the non-SGHD group (p = 0.045), and BMISDS is a significant factor for higher SBP in SGHD patients but not in non-sgHD patients. Expand
SHORT syndrome in two Chinese girls: A case report and review of the literature
SHORT syndrome is a rare inherited multisystem disease that includes characteristic facial features, growth retardation, and metabolic anomalies and is related to heterozygous mutations in the PIK3R1Expand
Etiologic and diagnostic analysis of 270 children with short stature in China Jining region
TLDR
The etiologies of children with short stature of Shandong Jining region are complex, and the correct diagnosis and appropriate treatment is very important. Expand
The research of prevalence of short stature of children and adolescents aged from 6 to 16 years in Jining
TLDR
The height of male in 2014 in Jining region is significantly higher than that of female, but there are differences among different age stages of growth. Expand
Association between Insulin-Like Growth Factor-1 and Relative Skeletal Maturation: A Retrospective Cohort Study of Short Children and Adolescents
TLDR
There is a nonlinear relationship between IGF-1 and BA maturation in short children before and after growth hormone (GH) treatment, and these findings suggest that a low level of IGF- 1 may contribute to BA delay in shortChildren and adolescents. Expand
Low-density lipoprotein cholesterol levels are associated with insulin-like growth factor-1 in short-stature children and adolescents: a cross-sectional study
TLDR
This study demonstrated a nonlinear relationship between IGF-1 and LDL-C independent of other potential confounding factors, suggesting that circulating IGF- 1 may contribute to the regulation of LDL- C levels, thus meriting further investigation. Expand
Association between Growth Hormone-Insulin-Like Growth Factor-1 Axis Gene Polymorphisms and Short Stature in Chinese Children
TLDR
The heterozygous genotypes of rs12515480 and rs6873545 of GHR gene were associated with decreased risk of GHD in Chinese children, consistent with those expected from Hardy-Weinberg equilibrium. Expand
Association between systolic blood pressure and uric acid in Chinese children and adolescents with idiopathic short stature: a cross-sectional study
TLDR
This study found a nonlinear relationship between UA and SBP in Chinese children and adolescents with ISS and showed that SBP levels were associated positively with the rise of UA levels when the UA levels reached the inflection point. Expand
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