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The genes encoding the murine paired immunoglobulin-like receptors PIR-A and PIR-B are members of a novel gene family which encode cell-surface receptors bearing immunoreceptor tyrosine-based inhibitory motifs (ITIMs) and their non-inhibitory/activatory counterparts. PIR-A and PIR-B have highly homologous extracellular domains but distinct transmembrane and(More)
STUDY QUESTION During controlled ovarian stimulation (COS), does the duration of premature serum progesterone (P) elevation before administration of hCG affect the outcomes of IVF/ICSI embryo transfer (-ET) cycles? SUMMARY ANSWER The duration of the premature serum P elevation is inversely related to the clinical pregnancy rate of IVF/ICSI-ET cycles. (More)
OBJECTIVE To analyze the prevalence of intrauterine adhesion (IUA) formation in women undergoing transcervical resection (TCR) for submucous myomas. DESIGN Retrospective cohort study. SETTING Tertiary university hospital. PATIENT(S) One hundred fifty-three women undergoing TCR for submucous myomas were retrospectively analyzed. Among them, 132 women(More)
BACKGROUND Anti-Müllerian hormone (AMH) is a biomarker that predicts the number of antral follicles and is involved in follicle arrest for women with polycystic ovary syndrome (PCOS). We investigated the association between the characteristic hyperandrogenemia, insulin resistance (IR), AMH, and the morphology and size of ovaries for women with PCOS. (More)
BACKGROUND Decreased high-density lipoprotein cholesterol (HDL-C) and sex hormone-binding globulin (SHBG) levels, and the metabolic syndrome, are all closely associated with a higher prevalence of atherosclerotic cardiovascular disease. We investigated the association between HDL-C, SHBG and the metabolic syndrome in women with polycystic ovary syndrome(More)
OBJECTIVE To investigate the endometrial wound healing duration after a hysteroscopic surgery. DESIGN Prospective study. SETTING Tertiary university hospital. PATIENT(S) One hundred sixty-three women who underwent hysteroscopic surgeries for endometrial polyp (n = 37), submucous myoma (n = 65), uterine septum (n = 16), and intrauterine adhesion (IUA;(More)
OBJECTIVE To determine the efficiency of a single-dose and a multiple-dose protocol for GnRH antagonist administration. DESIGN Randomized clinical trial. SETTING University hospital, tertiary medical center. PATIENT(S) Sixty-one patients undergoing controlled ovarian stimulation (COS) and IVF/ICSI. INTERVENTION(S) COS with either a multiple-dose(More)
OBJECTIVE To examine changes in local cytokine production in the eutopic endometrium of adenomyosis after treatment with medroxyprogesterone acetate (MPA) and danazol. DESIGN Prospective cohort study. SETTING Tertiary university hospital. PATIENT(S) Twenty-four women with adenomyosis (study group) and 22 women without adenomyosis (control group). (More)
STUDY QUESTION What is the role of myostatin and its relationship with obesity, androgens and follistatin levels in women with polycystic ovary syndrome (PCOS)? SUMMARY ANSWERS: The myostatin level was positively correlated to the risk of abdominal obesity, but negatively associated with circulating levels of dehydroepiandrosterone sulfate (DHEAS) and(More)